06897nam 2202221z- 450 991055733660332120220111(CKB)5400000000042512(oapen)https://directory.doabooks.org/handle/20.500.12854/77126(oapen)doab77126(EXLCZ)99540000000004251220202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierThe Retina in Health and DiseaseBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (465 p.)3-0365-2653-6 3-0365-2652-8 Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.Medicine and NursingbicsscNeurosciencesbicssc3,5-DHBAAc2-26African-Americanage-related macular degenerationAII amacrine cellaltricial bird speciesAlzheimer's diseaseAMDamyloidangiogenesisangiographyantioxidantsapoptosisarteriolesastrocytesATPatypical cannabinoid receptorsautophagyaxonbetulinic acidbioenergeticsbiomarkerblackcatalaseCD4+CD25+cellular senescenceCharles Bonnet syndromeclinical trialscognitive declinecomplement cascadecomplicationdevelopmentdiabetesdiabetes mellitusdiabetic retinopathydLGNDrp1early detectioneccentricityEEGelectron microscopyelectroretinographyendoplasmic reticulumepidermal growth factorexendin-4experimental modelseyeeye inflammationfingolimodFPR receptorfunctional analysisgap junctiongerm-free miceGFAPglucagon-like peptide-1GPR81growth coneGRP78gut microbiomegut-retina axisHCAR1HDAChigh-fat diethistone deacetylasehyperglycemiahypoxiaimmunodeficient RCS ratimmunohistochemistryinflammationinflammatory mediatorsiPSCiPSC-RPEischemia-reperfusion injurykallikrein-kinin systemkinin receptorslactateLED screenlight damagelipopolysaccharidemacrogliamesenchymal stem cellsmetabolismmicrogliamicroglia morphotypemicrovascularmicrovascular complications and dysfunctionmitochondriamonkeysmotor proteinMüller cellsmultiple sclerosismyosin 1Cn/anatural bioactive extractsneurodneurodegenerationneuroprotectionneurovascular unitNotchON/OFF asymmetryoptic nerve crushoptic neuritisoptical coherence tomographyoptical filterosteopontinouter segmentsoxidative stressparvalbuminphotoreceptorphotoreceptorsprecocial bird speciesprogenitor cellprogrammed cell deathProx1reactive oxygen speciesregenerationremodelingrespirationresting stateretinaretinal degenerationretinal degenerative diseasesretinal detachmentretinal fluorescence imagingretinal ganglion cellsretinal glial cellretinal inflammationretinal light injuryretinal microgliaretinal pigment epitheliumretinal protectionretinal transplantationretinal vesselsretinogenesisretinopathyrhodopsinRNA sequencingsenescence-associated galactosidase activitysignal transducer and activator of transcription 3spinal cord injurystem cell therapystress responsesystemic diseasetrichostatin A (TSA)typical cannabinoid receptorsultrathin paryleneunfolded protein responsevascular endothelial growth factor (VEGF)vascularizationvisual functionvisual hallucinationvisual systemzebrafishMedicine and NursingNeurosciencesPtito Mauriceedt1290173Bouskila JosephedtPtito MauriceothBouskila JosephothBOOK9910557336603321The Retina in Health and Disease3021386UNINA