03330nam 2200841z- 450 991055733320332120231214133006.0(CKB)5400000000042547(oapen)https://directory.doabooks.org/handle/20.500.12854/76579(EXLCZ)99540000000004254720202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMeasurement Technologies for up- and Downstream BioprocessingBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (160 p.)3-0365-1150-4 3-0365-1151-2 This book is devoted to new developments in measurement technologies for upstream and downstream bioprocessing. The recent advances in biotechnology and bioprocessing have generated a number of new biological products that require more qualified analytical technologies for diverse process analytical needs. These includes especially fast and sensitive measurement technology that, early in the process train, can inform on critical process parameters related to process economy and product quality and that can facilitate ambitions of designing efficient integrated end-to-end bioprocesses. This book covers these topics as well as analytical monitoring methods based either on real-time or in-line sensor technology, on simple and compact bioanalytical devices, or on the use of advanced data prediction methods.Technology: general issuesbicssclactate biosensorenzyme electrodeoff-line monitoringscreen-printingat-line measurementin-line monitoringcell viabilitypredictionchromatogram fingerprintingfilamentous fungiPenicillium chrysogenumTrichoderma reesei Rut-C30HPLC-SECAAV-adeno-associated virusinsect cell-baculoviruscell culture monitoringdigital holographic microscopyprocess analytical technologypHpCO2off-gas measurementcarbon dioxidecell culturereferenceCHOautomated samplingbioprocessamino acidsvitaminsRaman spectroscopymammalian cell culturehigh-throughputscale-down technologiescation exchange chromatographymonitoringPATIgG titerreal-timeon-linenanoplasmonicAAV-adeno-associated virusgene therapydielectric spectroscopyTechnology: general issuesMandenius Carl-Fredrikedt1322900Mandenius Carl-FredrikothBOOK9910557333203321Measurement Technologies for up- and Downstream Bioprocessing3035237UNINA