03367nam 2200865z- 450 991055733320332120220111(CKB)5400000000042547(oapen)https://directory.doabooks.org/handle/20.500.12854/76579(oapen)doab76579(EXLCZ)99540000000004254720202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMeasurement Technologies for up- and Downstream BioprocessingBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (160 p.)3-0365-1150-4 3-0365-1151-2 This book is devoted to new developments in measurement technologies for upstream and downstream bioprocessing. The recent advances in biotechnology and bioprocessing have generated a number of new biological products that require more qualified analytical technologies for diverse process analytical needs. These includes especially fast and sensitive measurement technology that, early in the process train, can inform on critical process parameters related to process economy and product quality and that can facilitate ambitions of designing efficient integrated end-to-end bioprocesses. This book covers these topics as well as analytical monitoring methods based either on real-time or in-line sensor technology, on simple and compact bioanalytical devices, or on the use of advanced data prediction methods.Technology: general issuesbicsscAAV-adeno-associated virusAAV-adeno-associated virusamino acidsat-line measurementautomated samplingbioprocesscarbon dioxidecation exchange chromatographycell culturecell culture monitoringcell viabilityCHOchromatogram fingerprintingdielectric spectroscopydigital holographic microscopyenzyme electrodefilamentous fungigene therapyhigh-throughputHPLC-SECIgG titerin-line monitoringinsect cell-baculoviruslactate biosensormammalian cell culturemonitoringn/ananoplasmonicoff-gas measurementoff-line monitoringon-linePATpCO2Penicillium chrysogenumpHpredictionprocess analytical technologyRaman spectroscopyreal-timereferencescale-down technologiesscreen-printingTrichoderma reesei Rut-C30vitaminsTechnology: general issuesMandenius Carl-Fredrikedt1322900Mandenius Carl-FredrikothBOOK9910557333203321Measurement Technologies for up- and Downstream Bioprocessing3035237UNINA