02352nam 2200577z- 450 991055732470332120211118(CKB)5400000000042632(oapen)https://directory.doabooks.org/handle/20.500.12854/72994(oapen)doab72994(EXLCZ)99540000000004263220202111d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPhosphorus Along the Soil-Freshwater-Ocean ContinuumFrontiers Media SA20191 online resource (165 p.)2-88945-829-6 This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contactOceanography (seas)bicsscScience: general issuesbicsscbiogeochemistryEstuariesEutrophicationLakesMonitoringOceansPhosphorusRiversSoilOceanography (seas)Science: general issuesCade-Menun Barbara Jedt1307132Duhamel SolangeedtDodd Rosalind JedtLønborg ChristianedtParsons Chris TedtTaylor William DedtCade-Menun Barbara JothDuhamel SolangeothDodd Rosalind JothLønborg ChristianothParsons Chris TothTaylor William DothBOOK9910557324703321Phosphorus Along the Soil-Freshwater-Ocean Continuum3028683UNINA03015nam 2200469z- 450 991022005130332120210212(CKB)3800000000216264(oapen)https://directory.doabooks.org/handle/20.500.12854/59232(oapen)doab59232(EXLCZ)99380000000021626420202102d2016 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierSensory Hair Cell Death and RegenerationFrontiers Media SA20161 online resource (266 p.)Frontiers Research Topics2-88945-000-7 Sensory hair cells are the specialized mechanosensory receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and balance. Hair cells can be damaged due to such factors as aging, ototoxic chemicals, acoustic trauma, infection, or genetic factors. Loss of these hair cells lead to deficits in hearing and balance, and in mammals, such deficits are permanent. In contrast, non-mammalian vertebrates exhibit the capability to regenerate missing hair cells. Researchers have been examining the process of hair cell death and regeneration in animal models in an attempt to find ways of either preventing hair cell loss or stimulating the production of new hair cells in mammals, with the ultimate goal of finding new therapeutics for human sensorineural hearing and balance deficits. This has led to a wide array of research on sensory hair cells- such as understanding the factors that cause hair cell loss and finding agents that protect them from damage, elucidating the cell signaling pathways activated during hair cell death, examining the genes and cellular pathways that are regulated during the process of hair cell death and regeneration, and characterizing the functional sensory loss and recovery following acoustic or ototoxic insults to the inner ear. This research has involved cell and developmental biologists, physiologists, geneticists, bioinformaticians, and otolaryngologists. In this Research Topic, we have collated reviews of the past progress of hair cell death and regeneration studies and original research articles advancing sensory hair cell death and regeneration research into the future.NeurosciencesbicsscauditoryCell DeathCochleaHair cellsHearing LossNeuromastOtic developmentOtoprotectionototoxicityRegenerationNeurosciencesMichael E. Smithauth1284055Allison B. CoffinauthAndrew K. GrovesauthBOOK9910220051303321Sensory Hair Cell Death and Regeneration3019241UNINA