03994nam 2201021z- 450 991055729110332120231214133603.0(CKB)5400000000041128(oapen)https://directory.doabooks.org/handle/20.500.12854/69153(EXLCZ)99540000000004112820202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMycobacterium tuberculosis Pathogenesis, Infection Prevention and TreatmentBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (128 p.)3-03936-658-0 3-03936-659-9 Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled “Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment” that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.Research & information: generalbicsscBiology, life sciencesbicsscMycobacterium tuberculosisline probe assaysecond-line drugsdrug resistanceXDR-TBMDR-TBomics analysisTB treatmentsystem analysisBeijing B0/W148Mycobacterium smegmatisimidazo[1,2-b][1,2,4,5]tetrazineMmpS5-MmpL5effluxdrug discoverytuberculosisimmune activationHLA-DRCD38treatment responseMycobacteriummacrophageapoptosiseffectorcytokinemicroRNABeijing genotypeCentral Asia Outbreakmurine infection modelVirulencepre-XDR-TBMycobacterium aviumunique metabolic pathwayssubtractive genomicsdrug targetuncharacterized proteinsBM-MSCsMtbbone-homingstem cell nichelatent tuberculosisrelapseliposomesM. tuberculosishost-pathogen interactionsimmune responseantitubercular drug discoveryantitubercular treatmentsIL-18IL-18BPIL-18Rgene expressionResearch & information: generalBiology, life sciencesFerraris Davide Mariaedt1296151Miggiano RiccardoedtRizzi MenicoedtFerraris Davide MariaothMiggiano RiccardoothRizzi MenicoothBOOK9910557291103321Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment3023812UNINA