03970nam 2200961z- 450 991055728950332120210501(CKB)5400000000041145(oapen)https://directory.doabooks.org/handle/20.500.12854/69438(oapen)doab69438(EXLCZ)99540000000004114520202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierBiomaterial-Related InfectionsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (204 p.)3-03943-438-1 3-03943-439-X The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues' bio-integration.Medicinebicsscanodization processanti-inflammatory propertiesantimicrobial activityantimicrobial agentsantimicrobial efficiencyantimicrobial resistanceautoclavingbiocompatibilitybiofilmsbiointegrationCandidaCandida glabrataCandida spp.candidemiacandidiasiscaspofungincold atmospheric-pressure plasma jet (CAPJ)diabetesDNA double-strand breaksechinocandinselectrospinningEscherichia coligenotoxicity assessmenthyperglycemiain vivoinfectioninfection controlmechanical propertiesmedical devicesmetabolic disordermicafunginn/ananofibersnanotubesnatural compoundsoral biofilmPETpolyethylene terephthalateresistancescanning electron microscopysilver ions releasesilver nanoparticlesStreptococcus mutansTaguchi methodTi6Al4V implantstitanium alloytitanium dioxidetitanium dioxide nanotubeswettabilityXPSMedicineRodrigues Célia Fedt1324789Martins NatáliaedtRodrigues Célia FothMartins NatáliaothBOOK9910557289503321Biomaterial-Related Infections3036301UNINA