02695nam 2200697z- 450 991055713580332120231214133417.0(CKB)5400000000040695(oapen)https://directory.doabooks.org/handle/20.500.12854/68341(EXLCZ)99540000000004069520202105d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierFeatures of Pathogenesis of Human Viral Infections and Antiviral DrugsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (84 p.)3-03943-917-0 3-03943-918-9 Among infectious diseases, viral infections are the leading cause of death worldwide, especially in the most low-income countries, particularly in young children. Most of the human viruses are all well characterized in terms of structure, life-cycle, tropism, and associated primary pathologies, but many of the pathogenetic mechanisms underlying their ability to cause acute infection, persist or reactivate in the host and cause chronic and/or degenerative damage, and still need to be fully clarified. At the same time, it seems necessary to develop novel therapeutic approaches and rationale, and possibly more potent antiviral compounds that are addressed to novel targets.MedicinebicsschRSVF geneG genechildrenrespiratory diseasesgenotypingSaudi Arabiaα chemokine receptor 4β-chemokine receptor 5human immunodeficiency virusmonocyte-derived macrophagesHPVsexually transmitted diseases (STDs)laboratory methodsPCRgenotypessurveillanceepidemiologyexopolysaccharideslactic acid bacteriahuman adenovirus type 5antiviral activitycell cycleprevalencehepatitis B virusgenotypebahrainsRAGEoxidative stressinflammationwartsMedicineAquaro Stefanoedt1278688Aquaro StefanoothBOOK9910557135803321Features of Pathogenesis of Human Viral Infections and Antiviral Drugs3013733UNINA