03818nam 2201141z- 450 991055710470332120210501(CKB)5400000000041000(oapen)https://directory.doabooks.org/handle/20.500.12854/69082(oapen)doab69082(EXLCZ)99540000000004100020202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPathogenesis and Treatment of Chronic PruritusBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (144 p.)3-03943-100-5 3-03943-101-3 This Special Edition Issue on the "Pathogenesis and Treatment of Chronic Pruritus" contains an overview of various known causes of chronic pruritus and emerging therapeutics. Chronic pruritus is an itch that lasts longer than six weeks, and is associated with a variety of dermatologic, systemic, neurologic, and psychiatric etiologies. Itch negatively impacts patient quality of life, and has devastating psychosocial consequences. The manuscripts published in this Special Issue are also a showcase of the current understanding of the pathogenesis of chronic pruritus, along with its epidemiology, diagnostic workup, and therapeutic approaches used to treat chronic pruritus. A special focus is also placed on prurigo nodularis, a severely pruritic chronic inflammatory skin disease.Medicine and Nursingbicsscantidepressantantihistaminergicaprepitantassociationsatopicatopic dermatitiscancerCav3.2 calcium channelcell signalingceramidechildrenchronicchronic prurituschronic pruritus of unknown origincomorbiditiesdemographicsdermatitisdisease burdendrug-induceddupilumabEGFReosinophilic dermatosis of hematologic malignancyepidemiologyepidermal growth factor receptorerlotinibgenderIL-13IL-4inpatiention channelsitchitch in woundsitch managementlichen planuslymphomalymphomatoid papulosismalignancymedical dermatologymedication-relatedmirtazapinemycosis fungoidesnational inpatient sampleneoplasmneurokinin1-receptorneuropathyNK1Rnodular prurigonodularisnoradrenergicpathogenesispediatricpine tarprurigoprurigo nodularisprurituspsoriasisraceracial differencesrefractoryRT-PCRserotonergicskinsystematic reviewtherapeutictreatmenturemic prurituswoundsMedicine and NursingKwatra Shawn Gedt1296133Kwatra Shawn GothBOOK9910557104703321Pathogenesis and Treatment of Chronic Pruritus3023793UNINA