03781nam 2201129z- 450 991055710470332120231214133610.0(CKB)5400000000041000(oapen)https://directory.doabooks.org/handle/20.500.12854/69082(EXLCZ)99540000000004100020202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPathogenesis and Treatment of Chronic PruritusBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (144 p.)3-03943-100-5 3-03943-101-3 This Special Edition Issue on the “Pathogenesis and Treatment of Chronic Pruritus” contains an overview of various known causes of chronic pruritus and emerging therapeutics. Chronic pruritus is an itch that lasts longer than six weeks, and is associated with a variety of dermatologic, systemic, neurologic, and psychiatric etiologies. Itch negatively impacts patient quality of life, and has devastating psychosocial consequences. The manuscripts published in this Special Issue are also a showcase of the current understanding of the pathogenesis of chronic pruritus, along with its epidemiology, diagnostic workup, and therapeutic approaches used to treat chronic pruritus. A special focus is also placed on prurigo nodularis, a severely pruritic chronic inflammatory skin disease.MedicinebicsscdupilumabIL-4IL-13prurituschronic pruritus of unknown originprurigo nodularisuremic prurituslichen planuseosinophilic dermatosis of hematologic malignancychronic pruritusmirtazapinechronicitchrefractorytreatmentnoradrenergicserotonergicantihistaminergicantidepressantskinatopic dermatitisceramidepine tardrug-inducedmedication-relatedepidemiologyinpatientdisease burdennational inpatient samplemedical dermatologysystematic reviewprurigonodularisatopicdermatitisracegendercomorbiditiesdemographicspediatricchildrenmalignancycancerneoplasmion channelscell signalingCav3.2 calcium channelRT-PCRwoundsitch in woundsitch managementaprepitanterlotinibEGFRepidermal growth factor receptorNK1Rneurokinin1-receptormycosis fungoidespsoriasisassociationslymphomatoid papulosislymphomaracial differencesnodular prurigoneuropathytherapeuticpathogenesisMedicineKwatra Shawn Gedt1296133Kwatra Shawn GothBOOK9910557104703321Pathogenesis and Treatment of Chronic Pruritus3023793UNINA