04182nam 2200481 450 991055420700332120230823002638.03-86859-951-710.1515/9783868599510(CKB)4100000011789043(DE-B1597)576513(DE-B1597)9783868599510(MiAaPQ)EBC6661560(Au-PeEL)EBL6661560(OCoLC)1241099707(EXLCZ)99410000001178904320220319d2020 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierAdaptive re-use strategies for post-war modernist housing /edited by Maren Harnack, Natalie Heger, Matthias BrunnerBerlin :Jovis,[2020]©20201 online resource (144 p.)3-86859-611-9 Frontmatter -- Contents -- Introduction -- Larger_Taller_Denser Post-War Modernist Housing in the Stuttgart Region -- Large-Scale Heritage A Conservation Perspective on Late Modernist Housing -- Highly Visible & Highly Valuable Big Housing Estates of the Boom Years -- Multi-Storey Housing in Britain A Historical and Heritage Overview -- The Crux of Inward Development -- Maintenance, Repair, and Renovation of the Finnish Post-War Housing Stock -- Wolfsburg Preserving Urban Design in Neighbourhoods Built Between 1938 and 1968 -- Future Prospects for the Neue Vahr An Interdisciplinary Approach to Drafting a Leitbild -- Conservation or Replacement of Large Housing Estates? Experiences from Bijlmermeer, Amsterdam, the Netherlands -- That’s How It Works! Replacing the Student Housing Complex in the Olympic Village, Munich -- Preserving the Legacy of Álvaro Siza -- Bremer Punkt -- Authors -- Image Credits -- ImprintIn florierenden Regionen stehen die Wohnungsmärkte unter erheblichem Druck. Will man Zersiedelung minimieren und Innenentwicklung fördern, scheinen Wohnsiedlungen der Nachkriegszeit prädestiniert für Nachverdichtung, da das Eigentum oft in den Händen einiger weniger Wohnungsbaugesellschaften liegt, die auch sozialen Wohnungsbau betreiben, und sie als eher wenig dicht wahrgenommen werden. Dabei besteht jedoch die Gefahr, dass die Siedlungen ihre charakteristischen Bau- und Freiraumstrukturen verlieren. Anhand europäischer Fallbeispiele von 1945 bis 1975 diskutiert Adaptive Re-Use Strategien zur Weiterentwicklung von Nachkriegssiedlungen. In den Beiträgen dieses Sammelbandes erfahren die Leser, wie Wohnsiedlungen aus verschiedenen europäischen Ländern denkmalpflegerisch bewahrt werden, wie die Gebäudestruktur an heutige Anforderungen angepasst werden kann und welche Strategien angewendet werden, um die Entwicklung von Siedlungen der Nachkriegsmoderne für die Zukunft zu sichern.In prosperous regions, housing markets are under significant pressure. With the focus on preserving land and developing brownfield sites, post-war housing estates are being earmarked for densification, as their density is perceived as rather low and the ownership is often concentrated in the hands of only a few publicly owned housing associations. In this setting, postwar estates are in danger of losing their characteristic spatial structures and landscaping. Adaptive Re-Use discusses strategies for the development of post-war housing by referring to European case studies from the period of 1945 to 1975. The contributions in this edited volume show how housing estates from different European countries are listed and preserved, and how architectural fabric can be adapted to meet today`s needs, while exploring the strategies applied to ensure the future development of large-scale housing.Architecture, Modern20th centuryArchitecture, Modern724.6Harnack MarenHeger NatalieBrunner MatthiasMiAaPQMiAaPQMiAaPQBOOK9910554207003321Adaptive re-use2817866UNINA05963nam 2200841Ia 450 991082916330332120200520144314.097866123432239781282343221128234322X9780470754221047075422297804707542140470754214(CKB)1000000000687468(EBL)470456(SSID)ssj0000288467(PQKBManifestationID)11222821(PQKBTitleCode)TC0000288467(PQKBWorkID)10373764(PQKB)10446491(Au-PeEL)EBL470456(CaPaEBR)ebr10300613(CaONFJC)MIL234322(FINmELB)ELB179501(OCoLC)264389508(MiAaPQ)EBC470456(Perlego)2750458(EXLCZ)99100000000068746820080318d2008 uy 0engur|n|---|||||txtccrAirway smooth muscle in asthma and COPD biology and pharmacology /edited by Kian Fan Chung1st ed.Hoboken, N.J. ;Chichester Wiley20081 online resource (332 p.)Description based upon print version of record.9780470060667 0470060662 Includes bibliographical references and index.Airway Smooth Muscle; Contents; List of Contributors; 1 Biophysical basis of airway smooth muscle contraction and hyperresponsiveness in asthma; 1.1 Introduction; 1.2 Airway hyperresponsiveness; 1.3 Classical behaviour of airway smooth muscle and the balance of static forces; 1.4 Shortening velocity and other manifestations of muscle dynamics; 1.5 Biophysical characterization of airway smooth muscle: bronchospasm in culture?; 1.6 Mechanical plasticity: a nonclassical feature of airway smooth muscle; 1.7 Recent observations; 1.8 Future directions; References2 Dynamics of cytoskeletal and contractile protein organization: an emerging paradigm for airway smooth muscle contraction2.1 Introduction; 2.2 Molecular structure and organization of contractile and cytoskeletal filaments in the airway smooth muscle cell; 2.3 Cytoskeletal dynamics and airway smooth muscle contraction; References; 3 Airway smooth muscle: role in airway constrictor hyperresponsiveness; 3.1 What is airway constrictor hyperresponsiveness (AHR)?; 3.2 Is AHR ever good?; 3.3 Potential mechanisms leading to airflow obstruction3.4 Potential abnormalities of airway smooth muscle (ASM)3.5 If ASM is dysfunctional, how did it get that way?; 3.6 Summary; Acknowledgements; References; 4 Airway smooth muscle phenotypic and functional plasticity; 4.1 Introduction; 4.2 Historical perspective: smooth muscle phenotype plasticity; 4.3 Features of phenotype plasticity; 4.4 Mechanisms for phenotypic plasticity; 4.5 Functional plasticity of airway smooth muscle: role in asthma pathogenesis; 4.6 Concluding remarks; References; 5 Airway smooth muscle proliferation: insights into mechanisms regulating airway smooth muscle mass5.1 Increases in airway smooth muscle (ASM) mass and the functional consequences5.2 Growth factors, inflammatory mediators and cytokines modulate ASM proliferation; References; 6 Airway smooth muscle bidirectional interactions with extracellular matrix; 6.1 Overview; 6.2 Introduction; 6.3 Airway extracellular matrix (ECM) in health and disease; 6.4 Integrins; 6.5 Airway smooth muscle (ASM) as a modulator of airway ECM; 6.6 Airway ECM as modulator of ASM function; 6.7 Impact of anti-asthma therapy on ASM-ECM interactions; 6.8 Conclusions; Acknowledgements; References7 Airway smooth muscle interaction with mast cells7.1 Introduction; 7.2 Mast cell mediators alter smooth muscle function; 7.3 Smooth muscle cells induce mast cell chemotaxis; 7.4 Mast cells can adhere to airway smooth muscle; 7.5 Conclusion; Acknowledgements; References; 8 Airway smooth muscle synthesis of inflammatory mediators; 8.1 Introduction; 8.2 Lipid mediators; 8.3 Chemokines; 8.4 Growth and remodelling factors; 8.5 Conclusions; References; 9 Airway smooth muscle in experimental models; 9.1 Introduction; 9.2 Methods of assessment of airway smooth muscle (ASM) function9.3 Potential mechanisms by which ASM properties may contribute to airway responsivenessIn this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. AuthoriRespiratory musclesPhysiologySmooth musclePhysiologyRespiratory musclesMolecular aspectsSmooth muscleMolecular aspectsRespiratory agentsRespiratory organsDiseasesTreatmentRespiratory therapyRespiratory musclesPhysiology.Smooth musclePhysiology.Respiratory musclesMolecular aspects.Smooth muscleMolecular aspects.Respiratory agents.Respiratory organsDiseasesTreatment.Respiratory therapy.616.2Chung K. Fan1951-879011MiAaPQMiAaPQMiAaPQBOOK9910829163303321Airway smooth muscle in asthma and COPD4014094UNINA