04345nam 22006975 450 991050266610332120251113180011.03-030-85536-810.1007/978-3-030-85536-9(CKB)4100000012026398(MiAaPQ)EBC6726393(Au-PeEL)EBL6726393(OCoLC)1268325517(PPN)258058609(DE-He213)978-3-030-85536-9(EXLCZ)99410000001202639820210913d2021 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierCardiomyocytes in Health and Disease /by Chandrasekharan C. Kartha1st ed. 2021.Cham :Springer International Publishing :Imprint: Springer,2021.1 online resource (356 pages)Biomedical and Life Sciences Series3-030-85535-X Includes bibliographical references and index.Section I: Normal Cardiomyocyte and its Growth -- 1. Structure and Function of Cardiomyocyte -- 2. Development of Cardiomyocyte -- 3. Cell Cycle Regulation in Cardiomyocytes -- 4. Cardiac Fibroblast and Cardiomyocyte Growth -- 5. Role of Endocardium and Epicardium in Generation of Cardiomyocytes -- Cardiomyocytes in the Mammalian Adult Heart -- 7. Energy Metabolism in Cardiomyocytes -- Section II: Cardiomyocyte Responses 8. Response of Cardiomyocytes to Mechanical Stress -- Cardiomyocyte Responses to Hormones 10. Sequelae of Genetic Defects in Cardiomyocytes -- 11. Response and Effects of Cardiomyocyte Progenitors in the Infarcted Heart -- Section III: Cardiomyocyte Aging and Death -- 12. Cardiomyocyte Senescence -- 13. Mechanisms of Cardiomyocyte Death -- 14. Cardiomyocyte Response to Ischemic Injury -- 15. Cardiomyocytes in Heart Failure -- Section IV: Cardiomyocyte Regeneration -- 16. Endogenous Mechanisms for Cardiomyocyte Regeneration -- 17. Mechanisms to Induce Cardiomyocyte Proliferation -- 18. Cell Sources of Cardiomyocytes for Heart Repair -- 19. Reprograming Fibroblasts for Cardiomyocytes and Progenitors -- Section V: Translational Aspects of Cardiomyocyte Biology -- 20. Clinical Translation of Discoveries in Cardiomyocyte Biology.This book is a treatise on cardiomyocytes, the most important cell for the contractile function of the heart. There has been significant progress in our understanding of the function-related structure, developmental processes and their determinants, mechanisms of cell cycle regulation, post-natal growth, energy metabolism, and reversible and irreversible response of cardiomyocytes to diverse forms of physiological stress and injury. There is also more clarity on the alterations in the biological mechanisms in cardiomyocytes that lead to pathological states and the changes in the cells that occur secondary to disease conditions. Thanks to these advances in knowledge, there have been great gains in attempts to identify disease biomarkers and therapeutic targets for better management of patients with heart diseases. Possibilities to induce regeneration or proliferation of cardiomyocytes and thus repair and or regenerate the damaged heart are also on the horizon. .Biomedical and Life Sciences SeriesCardiovascular systemPhysiologyCardiologyRegenerative medicineMedicineResearchBiologyResearchCardiovascular PhysiologyCardiologyRegenerative Medicine and Tissue EngineeringBiomedical ResearchCardiovascular system.Physiology.Cardiology.Regenerative medicine.MedicineResearch.BiologyResearch.Cardiovascular Physiology.Cardiology.Regenerative Medicine and Tissue Engineering.Biomedical Research.612.17Kartha C. Chandrasekharan1242084MiAaPQMiAaPQMiAaPQBOOK9910502666103321Cardiomyocytes in health and disease2881108UNINA03425oam 2200565I 450 991054769680332120241120175155.01-4822-5757-21-315-37234-71-315-35509-410.1201/9781315372341 (CKB)3710000000856803(MiAaPQ)EBC4683356(OCoLC)958377864(oapen)https://directory.doabooks.org/handle/20.500.12854/78437(ODN)ODN0004026691(ScCtBLL)91e2e421-843d-4775-970e-70d29ebab57a(EXLCZ)99371000000085680320180331h20172017 uy 0engurcnu||||||||rdacontentrdamediardacarrierGround improvement by deep vibratory methods /Klaus Kirsch, Fabian KirschSecond edition.Taylor & Francis2017Boca Raton :CRC Press,[2017]©20171 online resource (253 pages) illustrations1-4822-5756-4 Includes bibliographical references and index.1. An overview of deep soil improvement by vibratory methods -- 2. A history of vibratory deep compaction -- 3. Vibro compaction of granular soils -- 4. Improvement of fine-grained and cohesive soils by vibro replacement stone columns -- 5. Method variations and related processes -- 6. Environmental considerations -- 7. Contractual matters.Vibro compaction and vibro stone columns are the two dynamic methods of soil improvement most commonly used worldwide. These methods have been developed over almost eighty years and are now of unrivalled importance as modern foundation measures. Vibro compaction works on granular soils by densification, and vibro stone columns are used to displace and reinforce fine-grained and cohesive soils by introducing inert material. This second edition includes also a chapter on vibro concrete columns constructed with almost identical depth vibrators. These small diameter concrete piles are increasingly used as ground improvement methods for moderately loaded large spread foundations, although the original soil characteristics are only marginally improved. This practical guide for professional geotechnical engineers and graduate students systematically covers the theoretical basis and design principles behind the methods, the equipment used during their execution, and state of the art procedures for quality assurance and data acquisition. All the chapters are updated in line with recent developments and improvements in the methods and equipment. Fresh case studies from around the world illustrate the wide range of possible applications. The book concludes with variations to methods, evaluates the economic and environmental benefits of the methods, and gives contractual guidance.Soil stabilizationVibratory compactingFoundationsSoil stabilization.Vibratory compacting.Foundations.624.151363TEC005000TEC009020TEC009150bisacshKirsch Klaus524550Kirsch FabianFlBoTFGFlBoTFGBOOK9910547696803321Ground improvement by deep vibratory methods2788109UNINA