02207nas a2200397 i 450099100265510970753620231114120605.0011205m19999999us qr | |eng 1520-3972b11689559-39ule_instPERLE004711ExLCDU 90Journal of cold war studiesJournal of cold war studies. - 1999-Cambridge :MIT,1999-TrimestraleVol. 1, n. 1 (1999)- Codice CNR: E 00000346LE023 1999-2013; lac.: 2004;http://www.mitpressjournals.org/loi/jcwsE-journal (Publisher Site).b1168955907-04-2208-07-02991002655109707536LE023 Per. 900 JCW 1le023LE009 PER. STOR. 510pE0.00-no 180000.i1191966808-07-02LE023A.2005,V.71le023LE009 PER.STOR.510nE176.89-l- 180000.i1407483723-05-05LE023A.2004,V.51le023LE009 PER.STOR.510nE176.89-l- 180000.i1407809027-05-05LE023A.2006,V.81le023LE009 PER.STOR.510nE214.82-l- 180000.i1419594x21-02-06LE023A. 20071le023LE009 PER.STOR. 510nE214.82-l- 180000.i1441433830-03-07LE023v. 10 (2008)1le023LE009 PER.STOR.510nE214.82-no 180000.i1471094804-04-08LE023v. 11, 1-4 (2009)1le023LE009 PER.STOR. 510nE241.84-no 180000.i1495024806-04-09LE023v. 12, 1-4 (2010)1le023nE241.84-no 180000.i1512325x05-05-10LE023v. 13, n. 1-4 (2011)1le023nE244.70-no 180000.i1526830517-05-11LE023v. 14, n. 1-4 (2012)1le023nE256.26-no 180000.i1540931415-05-12LE023v. 15, n. 1-4 (2013)1le023nE376.49no 180000.i1562877231-07-14Journal of cold war studies. - 1999-3591524UNISALENTOle02301-01-01sa -engus 0103985nam 22007575 450 991050638210332120260213093407.03-030-85281-410.1007/978-3-030-85281-8(CKB)4950000000281514(MiAaPQ)EBC6785157(Au-PeEL)EBL6785157(OCoLC)1280048465(PPN)258297212(BIP)81923404(BIP)80998185(DE-He213)978-3-030-85281-8(EXLCZ)99495000000028151420211018d2021 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierBiophysical and Computational Tools in Drug Discovery /edited by Anil Kumar Saxena1st ed. 2021.Cham :Springer International Publishing :Imprint: Springer,2021.1 online resource (405 pages)Topics in Medicinal Chemistry,1862-247X ;373-030-85280-6 Kinetic profiling of fragments by TR-FRET -- Role of Structural biology in drug discovery with emphasis on X-ray crystallography -- A computational search for peptide vaccines using novel mathematical descriptors of sequences of emerging pathogens -- Solution NMR methods in Drug Discovery for the series -- Applications of Mass Spectrometry in Herbal Drug Research -- Generative machine learning for drug discovery -- Structure and ligand based virtual screening in drug discovery -- Quantum Chemical and Quantum Dynamics Techniques for Drug Discovery Including Bioinorganic Compounds.This book reviews recent physicochemical and biophysical techniques applied in drug discovery research, and it outlines the latest advances in computational drug design. Divided into 10 chapters, the book discusses about the role of structural biology in drug discovery, and offers useful application cases of several biophysical and computational methods, including time-resolved fluorometry (TRF) with Förster resonance energy transfer (FRET), X-Ray crystallography, nuclear magnetic resonance spectroscopy, mass spectroscopy, generative machine learning for inverse molecular design, quantum mechanics/molecular mechanics (QM/MM,ONIOM) and quantum molecular dynamics (QMT) methods. Particular attention is given to computational search techniques applied to peptide vaccines using novel mathematical descriptors and structure and ligand-based virtual screening techniques in drug discovery research. Given its scope, the book is a valuable resource for students, researchers and professionals frompharmaceutical industry interested in drug design and discovery.Topics in Medicinal Chemistry,1862-247X ;37Pharmaceutical chemistryPhysical biochemistryBiologyTechniqueChemistryData processingChemistry, Physical and theoreticalBiophysicsMedicinal ChemistryBiophysical ChemistryBiological TechniquesComputational ChemistryPhysical ChemistryBiophysical MethodsPharmaceutical chemistry.Physical biochemistry.BiologyTechnique.ChemistryData processing.Chemistry, Physical and theoretical.Biophysics.Medicinal Chemistry.Biophysical Chemistry.Biological Techniques.Computational Chemistry.Physical Chemistry.Biophysical Methods.615.1Saxena Anil KumarMiAaPQMiAaPQMiAaPQBOOK9910506382103321Biophysical and Computational Tools in Drug Discovery2025207UNINA04774nam 2200721Ia 450 991095764520332120260408012645.09786612169991978128216999912821699989783110198584311019858410.1515/9783110198584(CKB)1000000000691481(EBL)364684(OCoLC)437233361(SSID)ssj0000167731(PQKBManifestationID)11167716(PQKBTitleCode)TC0000167731(PQKBWorkID)10169914(PQKB)11656011(MiAaPQ)EBC364684(DE-B1597)34383(OCoLC)979635899(DE-B1597)9783110198584(Au-PeEL)EBL364684(CaPaEBR)ebr10256426(CaONFJC)MIL216999(Perlego)652928(EXLCZ)99100000000069148120070706d2007 uy 0engur|n|---|||||txtccrHandbook of intercultural communication /edited by Helga Kotthoff and Helen Spencer-Oatey1st ed.Berlin ;New York Mouton de Gruyterc20071 online resource (582 p.)Handbooks of applied linguistics ;v. 7Description based upon print version of record.9783110184716 3110184710 Includes bibliographical references and index.Frontmatter --Contents --1. Introduction --I. Multidisciplinary perspectives on intercultural communication --Editors' introduction --2. Discourse, cultural diversity and communication: a linguistic anthropological perspective --3. A cognitive pragmatic perspective on communication and culture --4. Psychological perspectives: social psychology, language, and intercultural communication --5. Emotion and intercultural adjustment --6. Multidisciplinary perspectives on intercultural conflict: the 'Bermuda Triangle' of conflict, culture and communication --II. Intercultural perspectives on communicative practices and processes --Editors' introduction --7. Intercultural communication and the relevance of cultural specific repertoires of communicative genres --8. Humour across cultures: joking in the multicultural workplace --9. Ritual and style across cultures --10. Lingua franca communication in multiethnic contexts --11. The impact of culture on interpreter behaviour --III. Intercultural communication in different sectors of life --Editors' introduction --12. Intercultural communication in healthcare settings --13. Differences and difficulties in intercultural management interaction --14. Understanding Aboriginal silence in legal contexts --15. Schools and cultural difference --16. The cultural context of media interpretation --17. Cross-cultural communication in intimate relationships --IV. Issues and Debates --Editors' introduction --18. Discrimination in discourses --19. Power and dominance in intercultural communication --20. Communicating Identity in Intercultural Communication --21. Communities of practice in the analysis of intercultural communication --V. Assessing and developing intercultural competence --Editors' introduction --22. Intercultural competence and assessment: perspectives from the INCA Project --23. Intercultural Training --24. Adapting authentic workplace talk for workplace intercultural communication training --BackmatterIn today's globalized world of international contact and multicultural interaction, effective intercultural communication is increasingly seen as a pre-requisite for social harmony and organisational success. This handbook takes a ?problem-solving? approach to the various issues that arise in real-life intercultural interaction. The editors have brought together experts from a range of disciplines, including linguistics, psychology and anthropology, to provide a multidisciplinary perspective on the field, whilst simultaneously anchoring it in Applied Linguistics. Key features: provides a stateHandbooks of applied linguistics ;v. 7.Intercultural communicationApplied linguisticsIntercultural communication.Applied linguistics.302.2AP 12750rvkKotthoff Helga1800870Spencer-Oatey Helen1952-1899914MiAaPQMiAaPQMiAaPQBOOK9910957645203321Handbook of intercultural communication4559528UNINA