02804nam 2200505 450 991048431520332120210227105304.0981-15-8327-710.1007/978-981-15-8327-8(CKB)4100000011493406(DE-He213)978-981-15-8327-8(MiAaPQ)EBC6370532(PPN)25830491X(EXLCZ)99410000001149340620210227d2021 uy 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierDevelopment of implantable electronics as novel approaches to obstructive sleep apnea /Jungmin Seo1st ed. 2021.Singapore :Springer,[2021]©20211 online resource (XVII, 75 p. 46 illus., 34 illus. in color.) Springer theses"Doctoral thesis accepted by Seoul National University, Korea."981-15-8326-9 Includes bibliographical references.Introduction -- Methods -- Results -- Discussions -- Conclusion. .This book addresses novel methods to treat a very popular disease, obstructive sleep apnea, based on a knowledge of an electrical engineering. Two approaches are given in the book using an upper-airway stimulation based on the pathogenesis of an obstructive sleep apnea. Implantable electronics are devised to control the tongue and the soft palate considering that they are the major pharyngeal muscles contributing to the apnea. First, for tongue control, a cuff electrode was designed and fabricated to stimulate the hypoglossal nerve, which innervates to the tongue muscle. Rare-earth magnets were embedded in the cuff for easy and repeatable installation of the electrode. For soft palate control, a palatal implant system was firstly developed to contract the soft palate muscle by applying electrical stimuli. Comprised of an implant, an intra-oral device, and an external controller, the palatal implant system is fully powered and controlled by means of wireless communication. The approaches were demonstrated in both in vitro and in vivo assessments, in collaboration with department of Otorhinolaryngology, Seoul National University Bundang Hospital. .Springer theses.Sleep apnea syndromesBiomedical engineeringSleep apnea syndromes.Biomedical engineering.616.209Seo Jungmin1226661MiAaPQMiAaPQMiAaPQBOOK9910484315203321Development of implantable electronics as novel approaches to obstructive sleep apnea2848234UNINA