03676nam 22006615 450 991048368120332120200701152708.03-540-29837-110.1007/3-540-29837-1(CKB)1000000000233211(EBL)3036329(SSID)ssj0000322734(PQKBManifestationID)11244388(PQKBTitleCode)TC0000322734(PQKBWorkID)10290262(PQKB)10076499(DE-He213)978-3-540-29837-3(MiAaPQ)EBC3036329(MiAaPQ)EBC6312879(EXLCZ)99100000000023321120110404d2002 u| 0engur|n|---|||||txtccrDrug Discovery and Evaluation: Pharmacological Assays[electronic resource] /edited by Hans G. Vogel2nd ed. 2002.Berlin, Heidelberg :Springer Berlin Heidelberg :Imprint: Springer,2002.1 online resource (1643 p.)Description based upon print version of record.3-540-33360-6 3-540-42396-6 Includes bibliographical references and index.""Preface to the first edition""; ""Contributors""; ""Contents""; ""Introduction Strategies in drug discovery and evaluation""; ""Chapter A Cardiovascular activity""; ""Chapter B Activity on blood constituents""; ""Chapter C Activity on urinary tract""; ""Chapter E Psychotropic and neurotropic activity""; ""Chapter F Drug effects on learning and memory""; ""Chapter G Effects on peripheral nerve function""; ""Chapter J Activity on the gastrointestinal tract""; ""Chapter K Antidiabetic activity""; ""Chapter M Anti- atherosclerotic activity""; ""Chapter N Endocrinology""""Chapter Q Guidelines for the care and use of laboratory animals""""Index""Now expanded and updated to include molecular biology and genetic engineering techniques! The 2nd edition of this successful reference book contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic respiratory, renal and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. The enclosed and fully searchable CD-ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.PharmacologyPharmacyBiochemistryPharmacology/Toxicologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21007Pharmacyhttps://scigraph.springernature.com/ontologies/product-market-codes/F00008Biochemistry, generalhttps://scigraph.springernature.com/ontologies/product-market-codes/L14005Pharmacology.Pharmacy.Biochemistry.Pharmacology/Toxicology.Pharmacy.Biochemistry, general.615.10724Vogel Hans Gedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910483681203321Drug discovery and evaluation512478UNINA