03652nam 2200625 450 991048348260332120220704133331.03-030-70107-710.1007/978-3-030-70107-9(CKB)5590000000486813(DE-He213)978-3-030-70107-9(MiAaPQ)EBC6640491(Au-PeEL)EBL6640491(OCoLC)1256541725(PPN)258062665(EXLCZ)99559000000048681320220203d2021 uy 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierCellular primary immunodeficiencies /Mario Milco D'Elios, Cosima Tatiana Baldari, Francesco Annunziato, editors ; foreword by Donatella Lippi1st ed. 2021.Cham, Switzerland :Springer,[2021]©20211 online resource (XIV, 513 p. 41 illus., 38 illus. in color.)Rare Diseases of the Immune System3-030-70106-9 1. Primary Immunodeficiencies -- 2. Genetics of Cellular Immunodeficiencies -- 3. Phenocopies of Primary Immuno Deficiencies -- 4. Dysfunctional immune synapses in T cell immunodeficiencies -- 5. Mucosal immunity in primary immunodeficiencies -- 6. Combined Immuno Deficiencies -- 7. Congenital defects of phagocytes -- 8. Defects in intrinsic and innate immunity -- 9. Diseases of immune dysregulation -- 10. IPEX syndrome and IPEX-related disorders -- 11. Autoinflammatory disorders -- 12. Lung in Cellular Immunodeficiencies -- 13. Gut involvement in Cellular Immunodeficencies -- 14. Malignancies in Cellular Immunodeficencies -- 15. Autoimmunity in Cellular Immunodeficencies -- 16. Differential diagnostic in Cellular Immunodeficiencies -- 17. Management of Cellular Immunodeficiencies -- 18. Vaccines in Cellular Immunodeficiencies -- 19. Gene therapy in Cellular Immunodeficiencies.This volume of the series Rare Diseases of the Immune System presents detailed state of the art knowledge on the cellular primary immunodeficiencies; it includes extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the T cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel cellular PID genes and related clinical applications, mucosal T cells, and the various clinical phenotypes of cellular PIDs. Cellular Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students.Rare diseases of the immune system.ImmunodeficiencyImmune systemCytopathologyImmunodeficiènciathubPatologia cel·lularthubSistema immunitarithubLlibres electrònicsthubImmunodeficiency.Immune systemCytopathology.ImmunodeficiènciaPatologia cel·lularSistema immunitari616.0473D'Elios Mario MilcoBaldari Cosima TatianaAnnunziato FrancesoLippi DonatellaMiAaPQMiAaPQMiAaPQBOOK9910483482603321Cellular Primary Immunodeficiencies2208975UNINA