02825nam 2200529 450 991048344000332120230717143732.03-030-62490-010.1007/978-3-030-62490-3(CKB)4100000011918836(DE-He213)978-3-030-62490-3(MiAaPQ)EBC6606062(Au-PeEL)EBL6606062(OCoLC)1250011614(PPN)255884982(EXLCZ)99410000001191883620220114d2021 uy 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierNext generation sequencing and data analysis /Melanie Kappelmann-Fenzl, editor1st ed. 2021.Cham, Switzerland :Springer,[2021]©20211 online resource (XII, 218 p. 54 illus., 51 illus. in color.)Learning materials in biosciences3-030-62489-7 Includes bibliographical references and index.Chapter 1. Next Generation Sequencing (NGS)- What can be sequenced? -- Opportunities and Perspectives of NGS Applications in Cancer Research -- Chapter 3. Library Construction for NGS -- Chapter 4. NGS Technologies -- Chapter 5. Computer Setup -- Chapter 6. Introduction to Command Line -- Chapter 7. NGS Data -- Chapter 8. Reference Genome -- Chapter 9. Alignment -- Chapter 10. Identification of Genetic Variants and de novo Mutations Based on NGS -- Chapter 11. Design and Analysis of RNA Sequencing Data -- Chapter 12. Design and Analysis of Epigenetics and ChIP-Sequencing Data -- APPENDIX.This textbook provides step-by-step protocols and detailed explanations for RNA Sequencing, ChIP-Sequencing and Epigenetic Sequencing applications. The reader learns how to perform Next Generation Sequencing data analysis, how to interpret and visualize the data, and acquires knowledge on the statistical background of the used software tools. Written for biomedical scientists and medical students, this textbook enables the end user to perform and comprehend various Next Generation Sequencing applications and their analytics without prior understanding in bioinformatics or computer sciences.Learning materials in biosciences.Sequence alignment (Bioinformatics)Biologia computacionalthubLlibres electrònicsthubSequence alignment (Bioinformatics)Biologia computacional572.8Kappelmann-Fenzl MelanieMiAaPQMiAaPQMiAaPQBOOK9910483440003321Next Generation Sequencing and Data Analysis2184191UNINA