02222nam 2200481 450 991046763560332120211110184331.01-119-51268-91-119-51264-6(CKB)4100000007520508(MiAaPQ)EBC5633950(Au-PeEL)EBL5633950(CaPaEBR)ebr11645471(OCoLC)1052905297(EXLCZ)99410000000752050820190129d2019 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierData monitoring committees in clinical trials a practical perspective /Susan S. Ellenberg, Thomas R. Fleming, David I. DeMetsSecond edition.Hoboken, NJ :Wiley,2019.1 online resource (493 pages)Statistics in practicePreceded by Data monitoring in committees in clinical trials : a practical perspective / Susan S. Ellenberg, Thomas R. Fleming, David L. DeMets. 2002.1-119-51265-4 Includes bibliographical references and index.Responsibilities of the data monitoring committee and motivating illustrations -- Composition of a data monitoring committee -- Independence of the data monitoring committee : avoiding conflicts of interest -- Confidentiality issues relating to the data monitoring committee -- Data monitoring committee meetings -- Data monitoring committee interactions with other trial components or related groups -- Statistical, philosophical and ethical issues in data monitoring -- Determining when a data monitoring committee is needed -- Regulatory considerations for the operation of data monitoring committees -- Legal considerations for DMCs.Statistics in practice.Electronic books.610.72/4Ellenberg Susan Smith850872Fleming Thomas R.DeMets David L.1944-MiAaPQMiAaPQMiAaPQBOOK9910467635603321Data monitoring committees in clinical trials1899789UNINA