05230nam 22007215 450 991046706500332120190326051319.03-11-047952-43-11-047985-010.1515/9783110479850(CKB)4100000001040907(MiAaPQ)EBC5144649(DE-B1597)466815(OCoLC)1004886209(OCoLC)1024010985(DE-B1597)9783110479850(EXLCZ)99410000000104090720190326d2017 fg engurcnu||||||||rdacontentrdamediardacarrierIron-Sulfur Clusters in Chemistry and Biology. Volume 2, Biochemistry, Biosynthesis and Human Diseases /Tracey Rouault2. Aufl.Berlin ;Boston : De Gruyter, [2017]©20171 online resource (492 pages) illustrationsIron-Sulfur Clusters in Chemistry and Biology ;Volume 23-11-047939-7 Includes bibliographical references at the end of each chapters and index.Frontmatter -- Preface -- Tracey A. Rouault biography -- Contents -- List of contributing authors -- 1 A retrospective on the discovery of [Fe-S] cluster biosynthetic machineries in Azotobacter vinelandii / Dos Santos, Patricia C. / Dean, Dennis R. -- 2 The ISC system and the different facets of Fe-S biology in bacteria / Aussel, Laurent / Chareyre, Sylvia / Duverger, Yohann / Ezraty, Benjamin / Huguenot, Allison / Mandin, Pierre / Py, Béatrice / Zamarreno, Jordi / Barras, Frédéric -- 3 A stress-responsive Fe-S cluster biogenesis system in bacteria - the suf operon of Gammaproteobacteria / Outten, F. Wayne -- 4 Sensing the cellular Fe-S cluster demand: a structural, functional, and phylogenetic overview of Escherichia coli IscR / Mettert, Erin L. / Perna, Nicole T. / Kiley, Patricia J. -- 5 Fe-S assembly in Gram-positive bacteria / Dos Santos, Patricia C. -- 6 Fe-S cluster assembly and regulation in yeast / Pain, Debkumar / Dancis, Andrew -- 7 The role of Fe-S clusters in regulation of yeast iron homeostasis / Outten, Caryn E. -- 8 Biogenesis of Fe-S proteins in mammals / Rouault, Tracey -- 9 Delivery of iron-sulfur clusters to recipient proteins: the role of chaperone and cochaperone proteins / Maio, Nunziata / Rouault, Tracey A. -- 10 Iron-sulfur proteins and human diseases / Tong, Wing Hang -- 11 Friedreich ataxia / Knight, Simon A. B. / Wilson, Robert B. -- 12 Connecting the biosynthesis of the molybdenum cofactor, Fe-S clusters, and tRNA thiolation in humans / Leimkühler, Silke -- 13 Iron-sulphur proteins and genome stability / Gari, Kerstin -- 14 Eukaryotic iron-sulfur protein biogenesis and its role in maintaining genomic integrity / Lill, Roland / Uzarska, Marta A. / Wohlschlegel, James -- 15 DNA signaling by iron-sulfur cluster proteins / Bartels, Phillip L. / O'Brien, Elizabeth / Barton, Jacqueline K. -- 16 Iron-sulfur cluster assembly in plants / Ye, Hong -- 17 Origin and evolution of Fe-S proteins and enzymes / Boyd, Eric S. / Schut, Gerrit J. / Shepard, Eric M. / Broderick, Joan B. / Adams, Michael W. W. / Peters, John W. -- IndexThis volume on iron-sulfur proteins includes chapters that discuss how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of iron sulfur proteins. In addition to their vital importance in mitochondrial respiration, numerous iron sulfur proteins are important in maintenance of DNA integrity. Multiple rare human diseases with different clinical presentations are caused by mutations of genes in the iron sulfur cluster biogenesis pathway. Understanding iron sulfur proteins is important for understanding a rapidly expanding group of metabolic pathways important in all kingdoms of life, and for understanding processes ranging from nitrogen fixation to human disease.Iron-sulfur proteinsElectronic books.Iron-sulfur proteins.574.19245Adams Michael W.W1053477Boyd Eric S1053478Broderick Joan B1053479Dancis Andy1053480Dean Dennis1053481Dos Santos Patricia1053482Gari Kerstin1053483Kiley Patricia1053484Leimkühler Silke1053485Lill Roland1053486Maio Nunziata1053487Mettert Erin L1053488Outten Caryn1053489Outten Wayne1053490Peters John1053491Shepard Eric M1053492Tong Wing Hang1053493Wohlschlegel James1053494Ye Hong1053495Rouault Tracey, DE-B1597DE-B1597BOOK9910467065003321Iron-Sulfur Clusters in Chemistry and Biology2485401UNINA