04820nam 2200661 450 991046610820332120200520144314.03-527-80015-8(CKB)3710000000616927(EBL)4451530(SSID)ssj0001683000(PQKBManifestationID)16508429(PQKBTitleCode)TC0001683000(PQKBWorkID)15037253(PQKB)10095136(MiAaPQ)EBC4451530(PPN)199263493(Au-PeEL)EBL4451530(CaPaEBR)ebr11174089(OCoLC)945137775(EXLCZ)99371000000061692720160324h20162016 uy| 0engur|n|---|||||txtccrReceptor biology /Michael F. Roberts and Anne E. KruhchtenWeinheim, Germany :Wiley-VCH Verlag GmBH & Company KGaA,[2016]©20161 online resource (478 p.)Description based upon print version of record.3-527-33726-1 Includes bibliographical references and index.Title Page; Copyright; Dedication; Table of Contents; Acknowledgments; Part I: Introduction; Chapter 1: Introduction; 1.1 Receptors and Signaling; 1.2 Types of Receptors and Hormones; 1.3 Receptors Are the Chemical Expression of Reality; Chapter 2: The Origins of Chemical Thinking; 2.1 Overview of Early Pharmacological History; 2.2 Modern Pharmacology; 2.3 Phylogenetics of Signaling; Part II: Fundamentals; Chapter 3: Membranes and Proteins; 3.1 Membranes; 3.2 The Nature and Function of Proteins; Chapter 4: Hormones as First Messengers; 4.1 Hormones and Cellular Communication4.2 Types of Hormones4.3 Vertebrate Hormones and Transmitters; 4.4 Analgesics and Venoms as Receptor Ligands; Chapter 5: Receptor Theory; 5.1 The Materialization of Receptors; 5.2 Receptor Mechanisms; 5.3 Binding Theory; 5.4 Visualizing Receptor Structure and Function; 5.5 Proteomics Approaches to Receptor Efficacy; 5.6 Physical Factors Affecting Receptor Binding; Part III: Receptor Types and Function; Chapter 6: Transduction I: Ion Channels and Transporters; 6.1 Introduction; 6.2 Small Molecule Channels; 6.3 Transporters; 6.4 Major Intrinsic Proteins; 6.5 Ligand-Gated Ion ChannelsChapter 7: Transduction II: G-Protein-Coupled Receptors7.1 Introduction; 7.2 Families of G-Protein-Coupled Receptors; 7.3 Transduction Mechanisms; 7.4 The Major Families of G Protein-Coupled Receptors; Chapter 8: Transduction III: Receptor Kinases and Immunoglobulins; 8.1 Protein Kinases; 8.2 Receptors for Cell Division and Metabolism; 8.3 Receptor Serine/Threonine Kinases; 8.4 The Guanylyl Cyclase Receptor Subfamily - Natriuretic Peptide Receptors; 8.5 Non-Kinase Molecules - LDL Receptors; 8.6 Cell-Cell Contact Signaling; 8.7 Immune System Receptors, Antibodies, and CytokinesChapter 9: Transduction IV: Nuclear Receptors9.1 Introduction; 9.2 Genomic Actions of Nuclear Receptors; 9.3 Actions of Receptor Antagonists; 9.4 Non-Traditional Actions of Steroid-Like Hormones and Their Receptors; Part IV: Applications; Chapter 10: Signaling Complexity; 10.1 Introduction; 10.2 Experimental Determination of Signaling Cascades; 10.3 Transduction across the Membrane; 10.4 Complexity in Cross Talk - Roles of PIP3, Akt, and PDK1; 10.5 Role in Cancer; 10.6 Signaling Mediated by Gas Molecules; Chapter 11: Cellular Interactions in Development; 11.1 Introduction11.2 The Origins of Multicellularity11.3 The Origin of Symmetry and Axes; 11.4 Fertilization and Organization of the Multicellular Body Plan; 11.5 Differentiation of Triploblastic Embryos - Organogenesis; 11.6 Programmed Cell Death (Apoptosis); Chapter 12: Receptor Mechanisms in Disease Processes; 12.1 Genetic Basis for Receptor Function; 12.2 Receptor Pathologies; 12.3 Signaling Mutations Leading to Cancer; Chapter 13: Receptors and the Mind; 13.1 Origins of Behavior; 13.2 Nervous Systems; 13.3 Animal Memory: Invertebrates; 13.4 Animal Memory: Vertebrates13.5 Receptors and Behavior: Addiction, Tolerance, and DependenceCell receptorsNuclear receptors (Biochemistry)Binding sites (Biochemistry)Ligands (Biochemistry)Electronic books.Cell receptors.Nuclear receptors (Biochemistry)Binding sites (Biochemistry)Ligands (Biochemistry)Roberts Michael F.78377Kruchten Anne E.MiAaPQMiAaPQMiAaPQBOOK9910466108203321Receptor biology2045653UNINA