05560nam 2200625 450 991046391000332120200520144314.092-4-069172-3(CKB)2670000000524345(EBL)1612008(SSID)ssj0001399223(PQKBManifestationID)11867877(PQKBTitleCode)TC0001399223(PQKBWorkID)11450623(PQKB)10983939(MiAaPQ)EBC1612008(Au-PeEL)EBL1612008(CaPaEBR)ebr10931291(OCoLC)870245961(EXLCZ)99267000000052434520140920h20132013 uy| 0engur|n|---|||||txtccrControl and surveillance of human African trypanosomiasis report of a WHO Expert Committee /World Health OrganizationGeneva, Switzerland :World Health Organization,[2013]©20131 online resource (249 p.)WHO technical report series,0512-3054 ;984"This report contains the collective views of an international group of experts and does not necessarily represent the decision or the stated policy of the World Health Organization"--T.p.92-4-120984-4 Includes bibliographical references.Cover; Contents; Abbreviations and acronyms; WHO Expert Committee on control and surveillance of human African trypanosomiasis; 1. Introduction; 2. Epidemiology of human African trypanosomiasis; 2.1 Two diseases, two parasites, two epidemiological patterns; 2.2 Transmission cycle; 2.2.1 Gambiense human African trypanosomiasis; 2.2.2 Rhodesiense human African trypanosomiasis; 2.3 Reservoirs of infection; 2.3.1 Gambiense human African trypanosomiasis; 2.3.2 Rhodesiense human African trypanosomiasis; 2.4 Risk factors for infection; 2.4.1 Gambiense human African trypanosomiasis2.4.2 Rhodesiense human African trypanosomiasis2.5 Trends in numbers of cases reported; 2.5.1 Gambiense human African trypanosomiasis; 2.5.2 Rhodesiense human African trypanosomiasis; 2.6 Geographical distribution and population at risk; 2.7 Global environmental change; 2.8 References; 3. The parasite; 3.1 Taxonomy of human infectious African trypanosomes; 3.2 Morphology and cell structure; 3.3 Life-cycle; 3.4 The Trypanosoma brucei genome; 3.5 Immune evasion; 3.6 Biochemistry and modes of drug action; 3.7 Drug resistance; 3.8 References; 4. The vector; 4.1 Classification4.1.1 Subgenus Nemorhina4.1.2 Subgenus Glossina s. str.; 4.1.3 Subgenus Austenina; 4.2 Reproductive system; 4.3 Reproduction; 4.4 Lifespan and population dynamics; 4.5 Diet; 4.6 Geographical distribution of the main vector species; 4.6.1 Vector species of the Nemorhina subgenus; 4.6.2 Vector species of the Glossina s. str. subgenus; 4.6.3 Vector species of the Austenina subgenus; 4.7 Tsetse flies in their natural environment; 4.7.1 Main habitats; 4.7.2 Movements; 4.7.3 Looking for hosts; 4.7.4 Feeding preferences; 4.7.5 Activity cycles; 4.7.6 Dispersal; 4.7.7 Resting places4.8 Population genetics and geometric morphometrics4.9 Genomics of tsetse flies; 4.10 Tsetse flies as cyclical vectors; 4.11 Vector control strategies; 4.11.1 Control; 4.11.2 Eradication; 4.11.3 Preliminary surveys; 4.12 Tsetse fly control methods; 4.12.1 Bush clearing; 4.12.2 Elimination of wild animal hosts; 4.12.3 Biological control of tsetse flies; 4.12.4 Autonomous control of tsetse flies; 4.12.5 Indigenous tsetse fly control practices; 4.12.6 Ground and aerial insecticide spraying; 4.12.7 Protecting zero grazing units by insecticide-impregnated netting; 4.12.8 Bait methods4.12.9 Olfactory baits (attractants) for tsetse flies4.12.10 Live baits; 4.12.11 Sterile insect technique; 4.13 New developments and outlook; 4.14 References; 5. The disease; 5.1 Gambiense human African trypanosomiasis: clinical signs and symptoms; 5.1.1 Lymphadenopathy; 5.1.2 Fever; 5.1.3 Headache; 5.1.4 Pruritus; 5.1.5 Musculoskeletal pain, hepatomegaly and splenomegaly; 5.1.6 Cardiac involvement; 5.1.7 Gastrointestinal symptoms; 5.1.8 Oedema; 5.1.9 Sleep disorder; 5.1.10 Neuropsychiatric symptoms and signs; 5.1.11 Endocrine disorders5.2 Rhodesiense human African trypanosomiasis: clinical signs and symptomsThis report provides information about new diagnostic approaches new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new information has formed the basis for an integrated strategy with which it is hoped that elimination of HAT will be achieved. The report also contains recommendations on the approaches that will lead to elimination of the disease.Human African Tryponosomiasis (HAT) is a disease that afflicts populationsTechnical report series (World Health Organization) ;984.TrypanosomiasisAfricaElectronic books.Trypanosomiasis614.5614.533WHO Expert Committee on Control and Surveillance of Human African Trypanosomiasis,MiAaPQMiAaPQMiAaPQBOOK9910463910003321Control and surveillance of human African trypanosomiasis2236359UNINA