03716nam 2200661 450 991046375570332120200520144314.00-19-937047-80-19-937048-60-19-992915-7(CKB)2670000000545519(EBL)1647165(OCoLC)874563137(SSID)ssj0001182829(PQKBManifestationID)11639815(PQKBTitleCode)TC0001182829(PQKBWorkID)11185042(PQKB)10589878(StDuBDS)EDZ0001446539(MiAaPQ)EBC1647165(Au-PeEL)EBL1647165(CaPaEBR)ebr10852029(CaONFJC)MIL584407(EXLCZ)99267000000054551920140329h20142014 uy 0engur|n|---|||||txtccrHuntington's disease /edited by Gillian Bates, Sarah Tabrizi and Lesley Jones ; Véronique M. André [and thirty seven others], contributorsFourth edition.New York :Oxford University Press,2014.©20141 online resource (513 p.)Oxford Monographs on Medical GeneticsDescription based upon print version of record.0-19-992914-9 Includes bibliographical references at the end of each chapters and index.""Cover""; ""Huntingtonâ€?s Disease""; ""Series""; ""Copyright""; ""Contents""; ""Contributors""; ""Section one Clinical Aspects of Huntingtonâ€?s Disease""; ""1 Huntingtonâ€?s Disease in a Historical Context""; ""2 Clinical Neurology""; ""3 Neuropsychiatry and Neuropsychology""; ""4 Juvenile Huntingtonâ€?s Disease""; ""5 Premanifest and Early Huntingtonâ€?s Disease""; ""Section two Genetics of Huntingtonâ€?s Disease""; ""6 Genetic and Molecular Studies""; ""7 Epidemiology""; ""8 Genetic Counseling and Testing""; ""Section three Neurobiology of Huntingtonâ€?s Disease""""9 Neuropathology in the Human Brain""""10 Altered Neuronal Circuitry""; ""Section Four Molecular Biology of Huntingtonâ€?s Disease""; ""11 Normal Function of Huntingtin""; ""12 Structural Biology: Order, Disorder, and Conformational Flux""; ""13 Pathogenic Mechanisms""; ""14 Peripheral Pathology""; ""Section five Therapeutic Interventions in Huntingtonâ€?s Disease""; ""15 Comprehensive Care""; ""16 Preclinical Experimental Therapeutics""; ""17 Experimental Therapeutics: Moving Forward in Clinical Trials""; ""Index""This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume are organized in five sections: DT Clinical aspects of Huntington's disease, including updated chapters on historical perspectives, neurological, neuropsychiatric, and neuropsychological aspects, and new chapters on juvenile Huntington's and the premanifest and early stages DT The genetics of HuntingtonOxford monographs on medical genetics.Huntington's choreaElectronic books.Huntington's chorea.616.85/1Bates GillianTabrizi SarahJones Lesley1957-André Véronique M.MiAaPQMiAaPQMiAaPQBOOK9910463755703321Huntington's disease2007245UNINA