05503nam 2200637 450 991046342850332120200520144314.00-323-22169-6(CKB)2670000000491166(EBL)1578348(OCoLC)865334943(SSID)ssj0001141543(PQKBManifestationID)11647392(PQKBTitleCode)TC0001141543(PQKBWorkID)11093164(PQKB)11543580(MiAaPQ)EBC1578348(PPN)184973767(Au-PeEL)EBL1578348(CaPaEBR)ebr10815296(CaONFJC)MIL550826(EXLCZ)99267000000049116620131223d2014 uy| 0engurcnu||||||||txtccrHandbook of polymer applications in medicine and medical devices /edited by Kayvon Modjarrad, MD, PhD, Chief, Respiratory Disease Vaccine Development, United States National Institutes of Health, Sina Ebnesajjad, PhD, President, FluoroConsultants Group, LLCOxford :William Andrew,2014.1 online resource (365 p.)PDL handbook seriesDescription based upon print version of record.0-323-22805-4 Includes bibliographical references and index.Front Cover; Handbook of Polymer Applications in Medicine and Medical Devices; Copyright Page; Contents; Preface; Author Biographies; 1 Introduction; 1.1 History; 1.2 A Historical Example; 1.3 Anthology Architecture; 1.4 Summary; References; 2 Application of Plastics in Medical Devices and Equipment; 2.1 Device Industry Overview; 2.2 Health-care Trends; 2.2.1 Minimally Invasive Surgeries; 2.2.2 Alternate Site Treatment; 2.2.3 Prevention vs. Treatment; 2.3 From Legacy Materials to Advanced Specialty Polymers for Devices; 2.4 Driving Trends Leading to New Material Requirements2.4.1 Functionality 2.4.2 Compatibility; 2.4.3 Cost; 2.4.3.1 Material Costs or Process Improvements; 2.4.3.2 Light Weighting; 2.4.3.3 Commoditizing Materials of Construction; 2.4.3.4 Technology Innovations; 2.4.4 Ecological and Environmental Concerns and Influence of the Consumer; 2.5 Market Factors Affecting the Industry; 2.5.1 Concerns Over DEHP and Sometimes Even PVC; 2.5.2 Bisphenol A; 2.5.3 The Need for "Green"; 2.5.4 Globalization of Markets; 2.5.5 Globalization of Manufacturing; 2.5.5.1 Energy Costs; 2.5.6 Global Influences; 2.5.6.1 Infectious Diseases (MRSA, SARS, H1N1)2.5.6.2 Economic Pressures 2.6 Conclusion; 3 Plastics Used in Medical Devices; 3.1 Plastic Compositions; 3.1.1 Polymer Properties; 3.1.1.1 Linear, Branched, and Cross-linked Polymers; 3.1.1.2 Isomers; Structural Isomers; Geometric Isomers; Stereoisomers-Syndiotactic, Isotactic, Atactic; 3.1.1.3 Molecular Weight; 3.1.2 Polymer Blends; 3.1.3 Additives; 3.1.3.1 Fillers, Reinforcement, Composites; 3.1.3.2 Release Agents; 3.1.3.3 Slip Additives/Internal Lubricants; 3.1.3.4 Catalysts; 3.1.3.5 Impact Modifiers and Tougheners; 3.1.3.6 Radiation Stabilizers; 3.1.3.7 Optical Brighteners3.1.3.8 Plasticizers 3.1.3.9 Pigments, Extenders, Dyes, Mica; 3.1.3.10 Coupling Agents; 3.1.3.11 Thermal Stabilizers; 3.1.3.12 Antistats; 3.2 Medical Devices-Material Selection Process; 3.2.1 Physical and Mechanical Properties; 3.2.2 Thermal Properties; 3.2.3 Electrical Properties; 3.2.4 Chemical Resistance; 3.2.5 Sterilization Capability; 3.2.6 Long-Term Durability; 3.2.7 Leachables and Extractables; 3.2.8 Supplemental Tests; 3.2.9 Shelf Life and Aging; 3.2.10 Joining and Welding; 3.2.11 Medical Grade Plastics; 3.3 Common Medical Device Polymers; 3.3.1 Polyethylene; 3.3.2 Polypropylene3.3.3 Polystyrene 3.3.4 Polyester; 3.3.5 Polyester (PLA and Other Biosorbable Plastics); 3.3.6 Polycarbonate; 3.3.7 Polyvinyl Chloride; 3.3.8 Polyethersulfone; 3.3.9 Polyacrylate (Acrylic, PMMA); 3.3.10 Hydrogel (Acrylate); 3.3.11 Polysulfone; 3.3.12 Polyetheretherketone; 3.3.13 Thermoplastic Elastomers (TPE, TPU); 3.3.14 Thermoset Elastomers-Silicone; 3.3.15 Poly-p-xylylene (Parylene); 3.3.16 Fluoropolymers; 3.4 Summary; References; 4 Polymeric Biomaterials; 4.1 Introduction; 4.2 Polymeric Biomaterials in Ophthalmology; 4.2.1 Polymeric Contact Lens; 4.2.2 Polymeric Intraocular Lens4.2.3 Polymeric Artificial CorneaWhile the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medicalPlastics Design LibraryPolymers in medicineElectronic books.Polymers in medicine.365Modjarrad Kayvon926361Ebnesajjad Sina494340MiAaPQMiAaPQMiAaPQBOOK9910463428503321Handbook of polymer applications in medicine and medical devices2079947UNINA