05731nam 22008893u 450 991046266080332120210108083325.0(CKB)2670000000332619(EBL)1667676(SSID)ssj0000585051(PQKBManifestationID)12264174(PQKBTitleCode)TC0000585051(PQKBWorkID)10593137(PQKB)10642477(MiAaPQ)EBC3329148(EXLCZ)99267000000033261920140414d2005|||| u|| |engurcnu---unuuutxtccrCentral Nervous System Tumours of Childhood /edited by Eddy Estlin and Stephen LowisLondon Mac Keith Press20051 online resource (372 p.)Clinics in developmental medicine,0069-4835 ;no.166Description based upon print version of record.1-898683-38-7 CONTENTS; AUTHORS' APPOINTMENTS; 1. INTRODUCTION Eddy Estlin and Stephen Lowis; REFERENCES; 2. THE EPIDEMIOLOGY OF PAEDIATRIC CNS TUMOURS GA Amos Burke; Incidence of primary CNS tumours; Age and site distribution of primary brain and spinal tumours; Incidence of secondary and metastatic tumours; Epidemiological evidence for aetiological factors in primary childhood brain; Tumour syndromes; Summary; REFERENCES; 3. PAEDIATRIC CNS TUMOURS: NEUROIMAGING Shelley Renowden; Neuroimaging techniques; Tumour types; REFERENCES4. PATHOLOGY AND MOLECULAR ONCOLOGY OF CHILDHOOD CNS TUMOURS Lucy B Rorke-Adams and Jaclyn A Biegel Neuroepithelial tumours; Non-neuroepithelial tumours; REFERENCES; 5. MOLECULAR APPROACHES TO THE UNDERSTANDING AND TREATMENT OF CHILDHOOD CNS TUMOURS Richard J Gilbertson; Advances in molecular biology techniques; Advances in pre-clinical disease models; Application of molecular biology to disease management; REFERENCES; Summary; 6. SURGICAL MANAGEMENT OF CNS TUMOURS IN THE PAEDIATRIC POPULATION Jerard Ross and John Thorne; General care; Perioperative managementSurgical roles in common tumoursAdjuncts to surgical management; The role of neuroendoscopy in tumour management; Epilepsy surgery; REFERENCES; 7. GENERAL PRINCIPLES OF RADIOTHERAPY Eddy Estlin and Stephen Lowis; Radiotherapy physics and biology; Techniques of radiotherapy administration; Side-effects of radiotherapy; Radiotherapy and the treatment of CNS tumours of childhood; Stereotactic radiosurgery in recurrent ependymoma; Conclusions and future directions; REFERENCES; 8. GENERAL PRINCIPLES OF CHEMOTHERAPY Eddy Estlin; Pharmacology and tumours of the CNS; Chemosensitivity and CNS tumoursClinical trials involving paediatric CNS tumoursRelationship between pharmacology, chemosensitivity and clinical effect; Summary and conclusions; REFERENCES; 9. MANAGEMENT OF COMPLICATIONS AT PRESENTATION FOR CHILDREN WITH CNS TUMOURS Stephen Lowis; Impaired consciousness, encephalopathy; Spinal cord compression; Electrolyte and endocrine disturbance; REFERENCES; 10. LOW-GRADE AND HIGH-GRADE ASTROCYTOMA Eddy Estlin and Stephen Lowis ; Low-grade glioma; High-grade astrocytoma; Conclusions; REFERENCES; 11. EPENDYMOMA Ute Bartels, Douglas J Hyder, Annie Huang and Eric BouffetHistopathological featuresMolecular biology and cytogenetic studies; Diagnostic features of intracranial ependymomas; Risk factors and prognostic considerations; Treatment; Recurrent ependymoma; Conclusions and further directions; REFERENCES; 12. BRAINSTEM TUMOURS Carolyn R Freeman and Jean-Pierre Farmer; Clinical presentation and imaging findings; Management; Prognosis; Controversies; REFERENCES; 13. PRIMITIVE NEUROECTODERMAL TUMOURS Stephen Lowis ; Pathology; Presentation; Assessment and staging; Prognostic factors; Therapy; Supratentorial PNET; Relapsed PNET; REFERENCES14. INTRACRANIAL GERM CELL TUMOURS Susanne J Rogers and Frank H SaranCovers all clinical aspects of central nervous system (CNS) tumours in children, including epidemiology and neuroimaging, the general principles of surgery and radiotherapy/chemotherapy as well as palliative care and quality of life. It also includes diagnosis and management, important areas of research which are important for clinical practice.Clinics in developmental medicine ;no. 166.Tumors in childrenTumorsCentral nervous systemNervous System NeoplasmsAge GroupsNeoplasms by SitePersonsNervous System DiseasesDiseasesNamed GroupsNeoplasmsCentral Nervous System NeoplasmsChildMedicineHILCCHealth & Biological SciencesHILCCOncologyHILCCElectronic books.Tumors in childrenTumorsCentral nervous systemNervous System NeoplasmsAge GroupsNeoplasms by SitePersonsNervous System DiseasesDiseasesNamed GroupsNeoplasmsCentral Nervous System NeoplasmsChildMedicineHealth & Biological SciencesOncology618.92/994Estlin EddyLowis StephenAU-PeELAU-PeELAU-PeELBOOK9910462660803321Central Nervous System Tumours of Childhood2277651UNINA