03213nam 2200601Ia 450 991046224850332120200520144314.0(CKB)2670000000234598(EBL)3408174(SSID)ssj0000874104(PQKBManifestationID)11470902(PQKBTitleCode)TC0000874104(PQKBWorkID)10887670(PQKB)10561541(MiAaPQ)EBC3408174(Au-PeEL)EBL3408174(CaPaEBR)ebr10588722(OCoLC)923413590(EXLCZ)99267000000023459819960313d1997 uy 0engur|n|---|||||txtccrAdvice to the serious seeker[electronic resource] meditations on the teaching of Frithjof Schuon /James S. CutsingerAlbany State University of New York Pressc19971 online resource (238 p.)SUNY series in Western esoteric traditionsDescription based upon print version of record.0-7914-3249-1 1-4384-0033-0 Includes bibliographical references (p. 219-220) and index.""Advice to the Serious Seeker: Meditations on the Teaching of Frithjof Schuon ""; ""Contents ""; ""Preface ""; ""Introduction: Landmarks on the Road Ahead ""; ""Chapter 1: The Way of Knowledge ""; ""Chapter 2: Thinking the Unthinkable ""; ""Chapter 3: Proofs of God ""; ""Chapter 4: The Intellect ""; ""Chapter 5: Degrees of Reality ""; ""Chapter 6: The Doctrine of Illusion ""; ""Chapter 7: The Open Door ""; ""Chapter 8: Conforming to God ""; ""Chapter 9: Perfection and Anonymity ""; ""Chapter 10: Humility ""; ""Chapter 11: Charity ""; ""Chapter 12: Veracity """"Chapter 13: Predestination and Freedom """"Chapter 14: A Space before God ""; ""Chapter 15: The World as Symbol ""; ""Chapter 16: The Message of the Human Body ""; ""Chapter 17: Sacred Art ""; ""Chapter 18: The Practice of Beauty ""; ""Chapter 19: Movement toward God ""; ""Chapter 20: Faith ""; ""Chapter 21: Method and Grace ""; ""Chapter 22: Concentration through Intention ""; ""Chapter 23: Invocation of the Name ""; ""Chapter 24: Spiritual Direction ""; ""Chapter 25: Our Final Goal ""; ""Epilogue: Perennial Philosophy and Transcendent Unity ""; ""Sources of Quotations """"Bibliography of Works by Frithjof Schuon """"Suggested Reading ""; ""Index ""; ""A ""; ""B ""; ""C ""; ""D ""; ""E ""; ""F ""; ""G ""; ""H ""; ""I ""; ""J ""; ""K ""; ""L ""; ""M ""; ""N ""; ""P ""; ""Q ""; ""R ""; ""S ""; ""T ""; ""U ""; ""V ""; ""W ""; ""Y ""; ""Z ""SUNY Series in Western Esoteric TraditionsSpiritual lifeMeditationsReligionsReligionElectronic books.Spiritual lifeReligions.Religion.200/.92Cutsinger James S.1953-922499MiAaPQMiAaPQMiAaPQBOOK9910462248503321Advice to the serious seeker2070082UNINA04511nam 22006015 450 991049215300332120251113173856.0981-16-0267-010.1007/978-981-16-0267-2(CKB)4100000011982479(MiAaPQ)EBC6678852(Au-PeEL)EBL6678852(PPN)258059397(OCoLC)1260292064(DE-He213)978-981-16-0267-2(EXLCZ)99410000001198247920210713d2021 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierAntiviral Drug Discovery and Development /edited by Xinyong Liu, Peng Zhan, Luis Menéndez-Arias, Vasanthanathan Poongavanam1st ed. 2021.Singapore :Springer Nature Singapore :Imprint: Springer,2021.1 online resource (364 pages)Advances in Experimental Medicine and Biology,2214-8019 ;1322981-16-0266-2 Includes bibliographical references.1 Antiviral Drugs Against Herpesviruses -- 2 An Update on Antiretroviral Therapy -- 3 Structural Insights to Human Immunodeficiency Virus (HIV-1) Targets and their Inhibition -- 4 LEDGINs, Inhibitors of the Interaction between HIV-1 Integrase and LEDGF/p75, are Potent Antivirals with a Potential to Cure HIV Infection -- 5 Moving Fast Towards Hepatitis B Virus Elimination -- 6 Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection -- 7 Phytoconstituents as Lead Compounds for Anti-dengue Drug Discovery -- 8 Anti-influenza Drug Discovery and Development: Targeting the Virus and its Host by all -- 9 Search, Identification and Design of Effective Antiviral Drugs against Pandemic Human Coronaviruses -- 10 Peptide Based Antiviral Drugs -- 11 Covalent Antiviral Agents -- 12 Safe-in-Man Broad Spectrum Antiviral Agents -- 13 Exploiting Ubiquitin ligases for Induced Target Degradation as an Antiviral Strategy. .This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.Advances in Experimental Medicine and Biology,2214-8019 ;1322PharmacologyPharmacyBiotechnologyPharmacologyPharmacyBiotechnologyPharmacology.Pharmacy.Biotechnology.Pharmacology.Pharmacy.Biotechnology.615.7924Liu XinyongMiAaPQMiAaPQMiAaPQBOOK9910492153003321Antiviral Drug Discovery and Development2072136UNINA