01159nam2-2200397---450 99000567869020331620210725201144.0000567869USA01000567869(ALEPH)000567869USA0100056786920051108d1971----|||y0itaa50------baitait0 00|||<<8: >> LettereDefinizioniDialoghi spuriPlatone[trad. di Antonio Maddalena]BariLaterza1971173 p.18 cm.0010005651502001Opere complete8BARI184PLATO292329MATHIEU,VittorioITSA20111219990005678690203316Dipar.to di Filosofia - SalernoDFFDC PLA OC 86646 FILXV.18.A. 996 8 (FDC PLA OC)6646 FILXV.18.A494145BKFDECI20121027USA01152620121027USA011615PATRY9020150410USA011427Dialoghi spuri90835Definizioni1084318Epistolai51807UNISA05582nam 22007333u 450 991046165100332120210108101615.00-470-97988-71-119-95766-4(CKB)2670000000176984(EBL)693297(OCoLC)784881826(SSID)ssj0000476918(PQKBManifestationID)11913382(PQKBTitleCode)TC0000476918(PQKBWorkID)10480289(PQKB)10535467(MiAaPQ)EBC693297(EXLCZ)99267000000017698420140106d2011|||| u|| |engur|n|---|||||txtccrBuilding Brains[electronic resource] An Introduction to Neural DevelopmentHoboken Wiley20111 online resource (350 p.)Description based upon print version of record.0-470-71229-5 Building Brains: An Introduction to Neural Development; Contents; Preface; Conventions and Commonly used Abbreviations; 1 Models and Methods for Studying Neural Development; 1.1 What is neural development?; 1.2 Why research neural development?; 1.2.1 The uncertainty of current understanding; 1.2.2 Implications for human health; 1.2.3 Implications for future technologies; 1.3 Major breakthroughs that have contributed to understanding developmental mechanisms; 1.4 Invertebrate model organisms; 1.4.1 Fly; 1.4.2 Worm; 1.4.3 Other invertebrates; 1.5 Vertebrate model organisms; 1.5.1 Frog1.5.2 Chick1.5.3 Zebrafish; 1.5.4 Mouse; 1.5.5 Humans; 1.5.6 Other vertebrates; 1.6 Observation and experiment: methods for studying neural development; 1.7 Summary; 2 The Anatomy of Developing Nervous Systems; 2.1 The nervous system develops from the embryonic neuroectoderm; 2.2 Anatomical terms used to describe locations in embryos; 2.3 Development of the neuroectoderm of invertebrates; 2.3.1 C. elegans; 2.3.2 Drosophila; 2.4 Development of the neuroectoderm of vertebrates and the process of neurulation; 2.4.1 Frog; 2.4.2 Chick; 2.4.3 Mouse; 2.5 Secondary neurulation in vertebrates2.6 Formation of invertebrate and vertebrate peripheral nervous systems2.6.1 Invertebrates; 2.6.2 Vertebrates: the neural crest and the placodes; 2.6.3 Vertebrates: development of sense organs; 2.7 Summary; 3 Neural Induction: An Example of How Intercellular Signalling Determines Cell Fates; 3.1 What is neural induction?; 3.2 Specification and commitment; 3.3 The discovery of neural induction; 3.4 A more recent breakthrough: identifying molecules that mediate neural induction; 3.5 Conservation of neural induction mechanisms in Drosophila3.6 Beyond the default model - other signalling pathways involved in neural induction3.7 Signal transduction: how cells respond to intercellular signals; 3.8 Intercellular signalling regulates gene expression; 3.8.1 General mechanisms of transcriptional regulation; 3.8.2 Transcription factors involved in neural induction; 3.8.3 What genes do transcription factors control?; 3.8.4 Gene function can also be controlled by other mechanisms; 3.9 The essence of development: a complex interplay of intercellular and intracellular signalling; 3.10 Summary; 4 Patterning the Neuroectoderm4.1 Regional patterning of the nervous system4.1.1 Patterns of gene expression are set up by morphogens; 4.1.2 Patterning occurs within a monolayer epithelium; 4.1.3 Patterning happens progressively; 4.2 Patterning the anteroposterior (AP) axis of the DrosophilaCNS; 4.2.1 Creating domains of transcription factor expression; 4.2.2 Dividing the ectoderm into segmental units; 4.2.3 Assigning segmental identity - the Hox code; 4.3 Patterning the AP axis of the vertebrate CNS; 4.3.1 Hox genes are highly conserved; 4.3.2 Initial AP information is imparted by the mesoderm4.3.3 Mesoderm signals set up domains of transcription factor expressionThe development of a brain from its simple beginnings in the embryo to the extraordinarily complex fully-functional adult structure is a truly remarkable process. Understanding how it occurs remains a formidable challenge despite enormous advances over the last century and current intense world-wide scientific research. A greater knowledge of how nervous systems construct themselves will bring huge benefits for human health and future technologies. Unravelling the mechanisms that lead to the development of healthy brains should help scientists tackle currently incurable diseases of the nervousDevelopmental neurobiologyNervous system --GrowthDevelopmental neurobiologyGrowthNervous systemNeuronsphysiologyNervous Systemanatomy & histologyNeurogenesisElectronic books.Developmental neurobiology.Nervous system --Growth.Developmental neurobiologyGrowthNervous systemNeuronsphysiology.Nervous Systemanatomy & histology.Neurogenesis.612.8Price David543765Jarman Andrew P878007Mason John O140119Kind Peter C882352AU-PeELAU-PeELAU-PeELBOOK9910461651003321Building Brains1970881UNINA