04553nam 2200541 a 450 991046130750332120200520144314.01-61324-474-6(CKB)2670000000095652(EBL)3019634(SSID)ssj0000522129(PQKBManifestationID)12179972(PQKBTitleCode)TC0000522129(PQKBWorkID)10527870(PQKB)10322412(MiAaPQ)EBC3019634(Au-PeEL)EBL3019634(CaPaEBR)ebr10671199(OCoLC)738478182(EXLCZ)99267000000009565220090625d2009 uy 0engur|n|---|||||txtccrDrug resistant neoplasms[electronic resource] /Ethan G. Verrite, editorNew York Nova Science Publishersc20091 online resource (269 p.)Cancer etiology, diagnosis and treatments seriesDescription based upon print version of record.1-60741-255-1 Includes bibliographical references and index.Therapeutic implications of the intrinsic and acquired resistance of cancer stem/progenitor cells in inefficacy of current cancer treatments and disease relapse / Murielle Mimeault and Surinder K. Batra -- Role of O6-methyl guanine-DNA methyl transferase and the effect of O6-benzylguanine in cancer chemotherapy / Jun Murakami ... [et al.] -- The role of tumoural micro-environment and its vasculature on chemotherapy drug resistance: the potential for it's modulation to achieve therapeutic gain / A. Weickhardt and M. Michael -- Inherent and microenvironment-mediated mechanisms of drug resistance / Malathy P.V Shekhar -- Studies on the mechanisms of acquired resistance to EGFR tyrosine kinase inhibitor gefitinib in NSCLC cell lines: evidence that ligand-induced endocytosis of EGFR via the early/late endocytic pathway is associated with gefitinib sensitivity of NSCLC cell line / Yukio Nishimura -- Mechanisms of resistance to EGF receptor-tyrosine kinase inhibitor in NSCLC cell lines: gefitinib sensitivity is closely correlated with ligand-induced endocytosis of phosphorylated EGF receptor / Yukio Nishimura, Kiyoko Yoshioka and Kazuyuki Itoh -- Targeting adverse features of hormone-resistant breast cancer / Stephen Hiscox ... [et al.] -- Systematic analysis of patterns of cross resistance between anticancer agents / Britta Stordal and Ross Davey -- Molecular structure and energy: clinical importance in drug resistant neoplasms / Viroj Wiwanitkit -- Treating drug resistant malignancy / Viroj Wiwanitkit -- Overcoming ovarian cancer drug resistance with phytochemicals and other compounds / Marion M. Chan and Dunne Fong -- New research communications on cancer drug resistance, assessment of cancer drug resistance with nuclear medicine images / Seigo Kinuya."One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumors, even those from the same tissue of origin. Frequently, resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common. The most common reason for acquisition of resistance to a broad range of anticancer drugs is expression of one or more energy-dependent transporters that detect and eject anticancer drugs from cells. Studies on the mechanisms of cancer drug resistance have yielded important information about how to circumvent this resistance to improve cancer chemotherapy and its implications for pharmacokinetics of many commonly used drugs. This book presents new and important research in this field"--Publisher's description.Cancer etiology, diagnosis, and treatments.Drug resistance in cancer cellsElectronic books.Drug resistance in cancer cells.616.99/4061Verrite Ethan G880482MiAaPQMiAaPQMiAaPQBOOK9910461307503321Drug resistant neoplasms1966055UNINA02633oam 2200565 450 991071656290332120210630090728.0(CKB)5470000002522525(OCoLC)1256818762(EXLCZ)99547000000252252520210617d2021 ua 0engurbn||||a||||txtrdacontentcrdamediacrrdacarrierBlocking property and suspending entry into the United States of certain persons contributing to the destabilizing situation in the Western Balkans communication from the President of the United States transmitting an executive order expanding the scope of the national emergency declared in Executive Order 13219 of June 26, 2001, as amended, pursuant to 50 U.S.C. 1703(b); Public law 95-223, Sec. 204(b); (91 Stat. 1627) and 50 U.S.C. 1641(b); Public law 94-412, Sec. 401(b); (90 Stat. 1257)Washington :U.S. Government Publishing Office,2021.1 online resource (6 pages)House document / 117th Congress, 1st session ;117-43"Referred to the Committee on Foreign Affairs.""June 11, 2021."Blocking property and suspending entry into the United States of certain persons contributing to the destabilizing situation in the Western Balkans Economic sanctions, AmericanBalkan PeninsulaTravel restrictionsUnited StatesPolitical violenceBalkan PeninsulaPreventionPolitical corruptionBalkan PeninsulaPeace-buildingBalkan PeninsulaNational securityBalkan PeninsulaNational securityUnited StatesUnited StatesForeign relationsBalkan PeninsulaBalkan PeninsulaForeign relationsUnited StatesLegislative materials.lcgftEconomic sanctions, AmericanTravel restrictionsPolitical violencePrevention.Political corruptionPeace-buildingNational securityNational securityBiden Joseph R.Jr.,United States.Congress.House.Committee on Foreign Affairs,GPOGPOOCLCOGPOBOOK9910716562903321Blocking property and suspending entry into the United States of certain persons contributing to the destabilizing situation in the Western Balkans3540959UNINA