05231nam 2200637 450 991046013530332120200520144314.01-118-88994-0(CKB)3710000000365738(EBL)1895710(SSID)ssj0001437628(PQKBManifestationID)12630170(PQKBTitleCode)TC0001437628(PQKBWorkID)11372766(PQKB)10927176(MiAaPQ)EBC1895710(DLC) 2015000334(Au-PeEL)EBL1895710(CaPaEBR)ebr11026086(CaONFJC)MIL770050(OCoLC)899267729(EXLCZ)99371000000036573820150310h20152015 uy 0engur|n|---|||||txtccrCardiovascular diseases from molecular pharmacology to evidence-based therapeutics /Y. Robert LiHoboken, New Jersey :John Wiley & Sons Inc.,2015.©20151 online resource (504 p.)Includes index.0-470-91537-4 Includes bibliographical references and index.Title Page; Copyright Page; Contents; Preface; List of Abbreviations; Unit I General Introduction; Chapter 1 Introduction to Cardiovascular Diseases; 1.1 Overview; 1.2 Definition of Cardiovascular Diseases; 1.3 Classification of Cardiovascular Diseases; 1.3.1 Classification Based on Anatomical Location; 1.3.2 Classification Based on the Involvement of Atherosclerosis; 1.3.3 Total Cardiovascular Diseases and ICD-10 Classification; 1.4 Prevalence, Incidence, and Trend of Cardiovascular Diseases; 1.4.1 NCDs and Cardiovascular Diseases: The Global Status1.4.2 The Status of Cardiovascular Diseases in the United States1.4.3 The Status of Cardiovascular Diseases in China; 1.5 Risk Factors of Cardiovascular Diseases; 1.5.1 Classification of Cardiovascular Disease Risk Factors; 1.5.2 Major Cardiovascular Disease Risk Factors and Their Impact; 1.6 Prevention and Control of Cardiovascular Diseases; 1.6.1 The UN High-Level Meeting and Tackling Cardiovascular Diseases at the Global Level; 1.6.2 The World Heart Federation Call to Action to Prevent and Control Cardiovascular Diseases1.6.3 The AHA 2010 Health Impact Goal, 2020 Health Impact Goal, and Ideal Cardiovascular Health1.6.4 US DHSS "Million Hearts" Initiative; 1.7 Cardiovascular Risk Prediction and Evidence-based Treatments; 1.7.1 Cardiovascular Risk Prediction; 1.7.2 Evidence-Based Treatments; 1.8 Summary of Chapter Key Points; 1.9 Self-Assessment Questions; References; Chapter 2 Introduction to Principles of Pharmacology; 2.1 Overview; 2.2 Definitions and History; 2.2.1 What Is Pharmacology?; 2.2.2 Definitions of Related Terms; 2.2.3 A Brief History of Pharmacology2.3 Pharmacological Paradigm: the Central Dogma in Pharmacology2.3.1 Drug Names, Sources, Preparations, and Administration; 2.3.2 Pharmacokinetics; 2.3.3 Pharmacodynamics; 2.3.4 Drug Toxicity; 2.3.5 Pharmacogenetics and Pharmacogenomics; 2.4 Principles of Drug Discovery, Development, and Regulation; 2.4.1 Definitions; 2.4.2 The Paradigm of Drug Creation and Survival; 2.4.3 The FDA Drug Review and Approval Process; 2.5 Pharmacology Subspecialties; 2.6 Introduction to Cardiovascular Pharmacology; 2.6.1 Definition and Scope; 2.6.2 New Developments and Challenges2.6.3 Systems Pharmacology in the Management of Cardiovascular Diseases2.6.4 Polypill for the Management of Cardiovascular Diseases; 2.6.5 Protein Therapeutics of Cardiovascular Diseases; 2.6.6 Gene Therapy of Cardiovascular Diseases; 2.6.7 Stem Cell Therapy of Cardiovascular Diseases; 2.7 Summary of Chapter Key Points; 2.8 Self-Assessment Questions; References; Unit II Dyslipidemias; Chapter 3 Overview of Dyslipidemias and Drug Therapy; 3.1 Introduction; 3.2 Lipoprotein Metabolism; 3.2.1 Definition, Structure, and Classification of Lipoproteins3.2.2 Metabolic Pathways of Lipoproteins and Drug TherapyWritten in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases. Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and treat cardiovascular diseases Facilitates understanding of drug action and mechanism by covering physiology / pathophysiology and pharmacology Includes guidelines and algorithms for pharmacCardiovascular systemDiseasesChemotherapyCardiovascular systemDiseasesDiagnosisElectronic books.Cardiovascular systemDiseasesChemotherapy.Cardiovascular systemDiseasesDiagnosis.616.1/061Li Robert Y.866523MiAaPQMiAaPQMiAaPQBOOK9910460135303321Cardiovascular diseases1934012UNINA