02500nam 2200601 a 450 991045978240332120200520144314.01-299-05316-51-60344-551-X(CKB)2670000000078948(OCoLC)654515885(CaPaEBR)ebrary10455993(SSID)ssj0000531046(PQKBManifestationID)11335437(PQKBTitleCode)TC0000531046(PQKBWorkID)10569477(PQKB)10750572(MiAaPQ)EBC3037918(MdBmJHUP)muse1146(Au-PeEL)EBL3037918(CaPaEBR)ebr10455993(CaONFJC)MIL436566(EXLCZ)99267000000007894820050607d2006 uy 0engurcn|||||||||txtccrThe Lena Goldfields massacre and the crisis of the late tsarist state[electronic resource] /Michael Melancon1st ed.College Station Texas A&M University Pressc20061 online resource (259 p.) Eugenia and Hugh M. Stewart '26 series on Eastern EuropeBibliographic Level Mode of Issuance: Monograph1-58544-508-8 Includes bibliographical references (p. [203]-232) and index.Introduction -- The early history of Lena gold mining -- Modern Lena gold mining, Lenzoto, and the workers, 1861-1912 -- The history of worker unrest in the Lena region, 1842-1912 -- The Lena Goldfields strike and shooting -- Politics, the strike committee, and competing discourses -- Unexpected consensus in Russian society -- Conclusion -- Appendix 1: Selected items from Lenzoto work contract for 1911-12 -- Appendix 2: Selected items from "our demands," submitted to Lenzoto, 3 March 1912.Eugenia and Hugh M. Stewart '26 series on Eastern Europe.Strikes and lockoutsGold miningRussia (Federation)Lena River ValleyMinersRussia (Federation)Lena River ValleyElectronic books.Strikes and lockoutsGold miningMiners957/.5Melancon Michael S.1940-866754MiAaPQMiAaPQMiAaPQBOOK9910459782403321The Lena Goldfields massacre and the crisis of the late tsarist state1934906UNINA03408nam 22005652 450 991045955700332120151005020622.00-511-84765-31-107-20737-10-511-64185-00-511-63941-40-511-64049-80-511-63834-50-511-64236-9(CKB)2610000000005671(MiAaPQ)EBC3004564(Au-PeEL)EBL3004564(CaPaEBR)ebr10356365(CaONFJC)MIL238668(OCoLC)593222021(UkCbUP)CR9780511642364(EXLCZ)99261000000000567120091012d2010|||| uy| 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierGene transfer and the ethics of first-in-human research lost in translation /Jonathan Kimmelman[electronic resource]Cambridge :Cambridge University Press,2010.1 online resource (xi, 205 pages) digital, PDF file(s)Title from publisher's bibliographic system (viewed on 05 Oct 2015).0-521-69084-6 0-521-87059-3 Includes bibliographical references and index.Introduction: gene transfer lost in translation -- What is gene transfer? -- Safety, values, and legitimacy: the protean nature of risk in translational trials -- Taming uncertainty: risk and gene-transfer clinical research -- Succor or suckers? Benefit, risk, and the therapeutic misconception -- Looking backward: a model value for translational trials -- The chasm: the ethics of initiating first-in-human clinical trials -- Tropic of cancers: gene transfer in resource-poor settings -- Great expectations and hard times: expectation management in gene transfer -- Something in the sight adjusts itself: conclusions.Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dimensions of testing interventions in human beings for the first time. The book discusses the difficult ethical challenges that arise from attempting to translate laboratory discoveries into clinical applications. These range from which available techniques to use, when to initiate human testing, questions of consent, expectation in public arenas, how to define acceptable risk, and the inclusion of vulnerable or disadvantaged subjects in early phase trials. This book is relevant to ethicists, legal practitioners, policy makers, geneticists and clinicians involved in clinical trials of new medical interventions.Gene Transfer & the Ethics of First-in-Human ResearchGene therapyMoral and ethical aspectsClinical trialsMoral and ethical aspectsGene therapyMoral and ethical aspects.Clinical trialsMoral and ethical aspects.615.8/95Kimmelman Jonathan1050649UkCbUPUkCbUPBOOK9910459557003321Gene transfer and the ethics of first-in-human research2480600UNINA01171nam a2200289 i 450099100067537970753620020507172122.0960612s1973 it ||| | ita b10741598-39ule_instLE01300548ExLDip.to Matematicaeng515.7248AMS 47H15Prodi, Giovanni8185Analisi non lineare /G. Prodi, A. AmbrosettiPisa Scuola Normale Superiore :1973171 p. ;23 cm.Pubblicazioni della Classe di Scienze. Quaderni ;1Equations involving nonlinear operatorsAmbrosetti, Antonioauthorhttp://id.loc.gov/vocabulary/relators/aut38493.b1074159823-02-1728-06-02991000675379707536LE013 47H PRO11 C.2 (1973)12013000050898le013-E0.00-l- 0120120.i1083284128-06-02LE013 47H PRO11 C.1 (1973)12013000057149le013-E0.00-l- 09090.i1083285328-06-02Analisi non lineare384288UNISALENTOle01301-01-96ma -itait 02