03008oam 2200625I 450 991045918950332120200520144314.00-429-19186-31-282-90323-397866129032361-58488-985-310.1201/9781584889854 (CKB)2670000000048176(EBL)599708(OCoLC)663999016(SSID)ssj0000423608(PQKBManifestationID)11281037(PQKBTitleCode)TC0000423608(PQKBWorkID)10468412(PQKB)10507151(MiAaPQ)EBC599708(Au-PeEL)EBL599708(CaPaEBR)ebr10424663(CaONFJC)MIL290323(EXLCZ)99267000000004817620180331d2010 uy 0engur|n|---|||||txtccrMultiple testing problems in pharmaceutical statistics /editors, Alex Dmitrienko, Ajit C. Tamhane, Frank BretzBoca Raton :Chapman & Hall/CRC/Taylor & Francis,2010.1 online resource (323 p.)Chapman & Hall/CRC biostatistics series ;33Description based upon print version of record.1-58488-984-5 Includes bibliographical references and index.Cover; Title; Copyright; Contents; Preface; List of Contributors; Chapter 1: Multiplicity Problems in Clinical Trials: A Regulatory Perspective; Chapter 2: Multiple Testing Methodology; Chapter 3: Multiple Testing in Dose-Response Problems; Chapter 4: Analysis of Multiple Endpoints in Clinical Trials; Chapter 5: Gatekeeping Procedures in Clinical Trials; Chapter 6: Adaptive Designs and Confirmatory Hypothesis Testing; Chapter 7: Design and Analysis of Microarray Experiments for Pharmacogenomics; Bibliography; IndexUseful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications. In each chapter, the expert contributors describe important multiplicity problems encountered in pre-clinical and clinChapman & Hall/CRC biostatistics series ;33.DrugsTestingStatistical methodsElectronic books.DrugsTestingStatistical methods.615/.1901Dmitrienko Alex858723Tamhane Ajit C102985Bretz Frank512836MiAaPQMiAaPQMiAaPQBOOK9910459189503321Multiple testing problems in pharmaceutical statistics1916812UNINA