05275nam 2200649Ia 450 991045875360332120200520144314.01-281-00348-497866110034870-08-047491-8(CKB)1000000000365177(EBL)291638(OCoLC)476050470(SSID)ssj0000152607(PQKBManifestationID)11151432(PQKBTitleCode)TC0000152607(PQKBWorkID)10340356(PQKB)11504884(MiAaPQ)EBC291638(Au-PeEL)EBL291638(CaPaEBR)ebr10172750(CaONFJC)MIL100348(EXLCZ)99100000000036517720070131d2007 uy 0engur|n|---|||||txtccrEye movements[electronic resource] a window on mind and brain /edited by Roger P.G. van Gompel ... [et al.]Amsterdam ;Oxford Elsevier20071 online resource (755 p.)Description based upon print version of record.0-08-044980-8 Includes bibliographical references and index.Front Cover; Eye Movements: A Window on Mind and Brain; Copyright Page; Table of Contents; Preface; List of Contributors; Reviewers; Chapter 1 Eye-Movement Research: An Overview of Current and Past Developments; Abstract; 1. Overview of the parts in this book; 2. Questionnaire study and journal database search; 3. Conclusions; References; PART 1: HISTORY OF EYE-MOVEMENT RESEARCH; Chapter 2 Scanning the Seen: Vision and the Origins of Eye-Movement Research; Abstract; 1. Visual vertigo; 2. Torsion; 3. Eye movements during reading; 4. Eye movements over patterns; 5. Conclusion; ReferencesChapter 3 Eye Movement Research in the 1950sAbstract; 1. Change in mindset; 2. Micronystagmus; 3. Systems theory; 4. Limitations to the approach; References; Chapter 4 Fixation Strategies During Active Behaviour: A Brief History; Abstract; 1. Introduction: before 1990; 2. The block copying task of Dana Ballard: Two useful maxims; 3. Everyday life tasks: making tea and sandwiches; 4. Ball games; 5. Driving; 6. Conclusions; References; PART 2: PHYSIOLOGY AND CLINICAL STUDIES OF EYE MOVEMENTS; Chapter 5 Using Eye Movements to Probe Development and Dysfunction; Abstract; 1. Introduction2. Overview of brain areas involved in saccade control3. Saccadic eye-movement tasks; 4. Accumulator models describe reaction times; 5. Normal Development; 6. Eye-Movement Abnormalities in clinical studies; 7. Attention Deficit Hyperactivity Disorder; 8. Parkinson's disease; 9. Tourette Syndrome; 10. Delayed saccade task; 11. Conclusions; Appendix A; References; Chapter 6 Anti-Saccade Task Performance is Dependent Upon Bold Activation Prior to Stimulus Presentation: An fMRI Study in Human Subjects; Abstract; 1. Methods; 2. Results; 3. Discussion; ReferencesChapter 7 Commutative Eye Rotations in Congenital NystagmusAbstract; 1. Listing's law; 2. Muscle pulleys; 3. Commutative eye movements and ocular motor instabilities; 4. Methods; 5. Results; 6. Discussion; Acknowledgement; References; PART 3: TRANSSACCADIC INTEGRATION; Chapter 8 Transsaccadic Recognition in Scene Exploration; Abstract; 1. Introduction; 2. The power of single-shot perception; 3. Transsaccadic information integration in scene exploration: The Pit and the Pendulum; 4. Some new data: Transsaccadic object recognition in scenes5. Conclusion: Time to put a transsaccadic theory of recognition on the agendaAcknowledgement; References; Chapter 9 How Postsaccadic Visual Structure Affects the Detection of Intrasaccadic Target Displacements; Abstract; 1. Experiment 1; 2. Experiment 2; 3. Experiment 3; 4. Experiment 4; 5. General discussion; Acknowledgements; References; Chapter 10 Transsaccadic Memory: Building a Stable World from Glance to Glance; Abstract; 1. Introduction; 2. Combining basic visual information across saccades; 3. Transsaccadic accumulation of memory for natural scenes4. The cost of transsaccadic integrationEye-movement recording has become the method of choice in a wide variety of disciplines investigating how the mind and brain work. This volume brings together recent, high-quality eye-movement research from many different disciplines and, in doing so, presents a comprehensive overview of the state-of-the-art in eye-movement research. Sections include the history of eye-movement research, physiological and clinical studies of eye movements, transsaccadic integration, computational modelling of eye movements, reading, spoken language processing, attention and scene perception, and eye-EyeMovementsCongressesEyeMovementsElectronic books.EyeMovementsEyeMovements.612.846Van Gompel Roger P. G918987European Conference on Eye MovementsMiAaPQMiAaPQMiAaPQBOOK9910458753603321Eye movements2061215UNINA04807nam 22006014a 450 991014371220332120170815115539.01-280-41112-097866104111220-470-03409-20-470-03324-X(CKB)1000000000357377(EBL)255725(OCoLC)161994171(SSID)ssj0000176910(PQKBManifestationID)11165722(PQKBTitleCode)TC0000176910(PQKBWorkID)10210102(PQKB)10443710(MiAaPQ)EBC255725(PPN)137628463(EXLCZ)99100000000035737720050923d2006 uy 0engur|n|---|||||txtccrImmunogenomics and human disease[electronic resource] /[edited by] András FalusChichester, West Sussex, England ;Hoboken, NJ John Wileyc20061 online resource (558 p.)Description based upon print version of record.0-470-01530-6 Includes bibliographical references and index.Immunogenomics and Human Disease; Contents; Preface; List of Contributors; 1 Genotyping methods and disease gene identification; 1.1 Introduction; 1.2 Genotyping of single-nucleotide polymorphisms; 1.3 Methods for interrogating SNPs; 1.4 Analysis formats; 1.5 The current generation of methods for SNP genotyping; 1.6 The next generation; 1.7 Classical HLA typing; 1.8 MHC haplotypes; 1.9 Molecular haplotyping; 1.10 Microhaplotyping; 1.11 MHC and disease associations; 1.12 Conclusions; Acknowledgements; References2 Glycomics and the sugar code: primer to their structural basis and functionality2.1 Introduction; 2.2 Lectins as effectors in functional glycomics; 2.3 Galectins: structural principles and intrafamily diversity; 2.4 Ligand-dependent levels of affinity regulation; 2.5 Perspectives for galectin-dependent medical applications; 2.6 Conclusions; References; 3 Proteomics in clinical research: perspectives and expectations; 3.1 Introduction; 3.2 Proteomics: tools and projects; 3.3 Discussion; 3.4 Concluding remarks; Acknowledgements; References4 Chemical genomics: bridging the gap between novel targets and small molecule drug candidates. Contribution to immunology4.1 Introduction of chemical genomics: definitions; 4.2 Chemical microarrays; 4.3 Small molecule and peptide probes for studying binding interactions through creating a covalent bond; 4.4 Photochemical proteomics; 4.5 General aspects of photoaffinity labelling; 4.6 Photoreactive probes of biomolecules; 4.7 Application to the immunobiology of living cells; 4.8 Multifunctional photoprobes for rapid analysis and screening; 4.9 Advanced application to functional proteomics4.10 SummaryReferences; 5 Genomic and proteomic analysis of activated human monocytes; 5.1 Primary human monocytes, as a model system; 5.2 Transcriptional profiling of activated monocytes; 5.3 Functional genomics; 5.4 Proteomic analysis of activated human monocytes; References; 6 Bioinformatics as a problem of knowledge representation: applications to some aspects of immunoregulation; 6.1 Introduction; 6.2 Sequences and languages; 6.3 Three-dimensional models; 6.4 Genomes, proteomes, networks; 6.5 Computational tools; 6.6 Information processing in the immune system; 6.7 Concluding remarksReferences7 Immune responsiveness of human tumours; 7.1 Introduction; 7.2 Defining tumour immune responsiveness; 7.3 Studying immune responsiveness in human tumours; 7.4 Immune responsiveness in the context of therapy; 7.5 The spatial dimension in the quest for the target; 7.6 Studying the receiving end - tumour as an elusive target for immune recognition; 7.7 The role of the host in determining immune responsiveness; 7.8 Concluding remarks; References; 8 Chemokines regulate leukocyte trafficking and organ-specific metastasis; 8.1 Chemokines and chemokine receptors8.2 Chemokine receptors in the organ-specific recruitment of tumour cellsThis book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.ImmunogeneticsImmunogenetics.616.0796616.979Falus András923310MiAaPQMiAaPQMiAaPQBOOK9910143712203321Immunogenomics and human disease2072063UNINA