04727nam 22005894a 450 991045609320332120200520144314.01-280-18534-197866101853440-309-56970-2(CKB)110986584753150(EBL)3377375(SSID)ssj0000284928(PQKBManifestationID)11912606(PQKBTitleCode)TC0000284928(PQKBWorkID)10261691(PQKB)10380620(MiAaPQ)EBC3377375(Au-PeEL)EBL3377375(CaPaEBR)ebr10071402(CaONFJC)MIL18534(OCoLC)923270163(EXLCZ)9911098658475315020000829d2000 ua 0engur|n|---|||||txtccrToxicological effects of methylmercury[electronic resource] /Committee on the Toxicological Effects of Methylmercury, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research CouncilWashington, DC National Academy Pressc20001 online resource (368 p.)Description based upon print version of record.0-309-07140-2 Includes bibliographical references.""Toxicological Effects of Methylmercury""; ""Copyright""; ""PREFACE""; ""Contents""; ""EXECUTIVE SUMMARY""; ""THE CHARGE TO THE COMMITTEE""; ""THE COMMITTEE'S APPROACH TO ITS CHARGE""; ""THE COMMITTEE'S EVALUATION""; ""Health Effects of Methylmercury""; ""Determination of the Critical Study for the RfD""; ""Estimation of Dose and Biological Variability""; ""Modeling the Dose-Response Relationships""; ""Public Health Implications""; ""RESEARCH NEEDS""; ""RECOMMENDATIONS""; ""1 INTRODUCTION""; ""SOURCES OF HG""; ""FATE AND TRANSPORT""; ""HEALTH EFFECTS""; ""EXPOSURE EVENTS AND STUDIES""""SUMMARY OF RISK ASSESSMENTS FOR MEHG""""SCIENTIFIC CONTROVERSIES AND SOURCES OF UNCERTAINTY""; ""ORGANIZATION OF THE REPORT""; ""REFERENCES""; ""2 CHEMISTRY, EXPOSURE, TOXICOKINETICS, AND TOXICODYNAMICS ""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""METHODS OF CHEMICAL ANALYSIS""; ""EXPOSURES TO MEHG IN THE U.S. POPULATION""; ""TOXICOKINETICS""; ""Absorption and Distribution""; ""Methylmercury""; ""Dimethylmercury""; ""Elemental Mercury""; ""Inorganic Mercury""; ""Biotransformation""; ""Excretion""; ""MOBILIZATION OF BODY HG""; ""CHEMICAL FORMS OF HG IN TOXICITY""""TOXIC EFFECTS AND TARGET ORGANS""""BIOCHEMICAL MECHANISMS OF TOXICITY""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""3 BIOLOGICAL VARIABILITY ""; ""AGE-RELATED SUSCEPTIBILITY""; ""GENDER DIFFERENCES""; ""GENETICS""; ""MECHANISMS OF NUTRITIONAL INFLUENCE ON MEHG HEALTH EFFECTS""; ""Dietary Interactions and Confounding""; ""Selenium""; ""Garlic""; ""Omega-3 Fatty Acids""; ""Protein""; ""Alcohol""; ""Other Foods That Might Influence Hg Uptake""; ""Vitamin E""; ""Nutrient Enhancement of Toxicity""; ""Beneficial Effects of Fish Consumption""; ""TOXICOKINETIC VARIABILITY""""CONCLUSIONS""""RECOMMENDATIONS""; ""REFERENCES""; ""4 DOSE ESTIMATION ""; ""DIETARY ASSESSMENT""; ""BIOMARKERS OF EXPOSURE""; ""Methylmercury in Blood""; ""Methylmercury in Hair""; ""Comparison of Biomarkers of Exposure""; ""ANALYTICAL ERROR IN BIOMARKER MEASUREMENTS""; ""EXPOSURE AND DOSE ASSESSMENT IN THE SEYCHELLES, FAROE ISLANDS, AND NEW ZEALAND STUDIES""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""5 HEALTH EFFECTS OF METHYLMERCURY ""; ""CARCINOGENICITY""; ""Human Studies""; ""Animal Studies""; ""GENOTOXICITY""; ""Human Studies""; ""Animal Studies""""In Vitro Studies""""IMMUNOTOXICITY""; ""Human Studies""; ""Animal Studies""; ""Effects on the Adult Immune System""; ""Effects on the Developing Immune System""; ""In Vitro Studies""; ""Autoimmune Response""; ""Human Studies""; ""Animal Studies""; ""REPRODUCTIVE EFFECTS""; ""Human Studies""; ""Animal Studies""; ""RENAL TOXICITY""; ""Human Studies""; ""Animal Studies""; ""CARDIOVASCULAR EFFECTS""; ""Human Studies""; ""Animal Studies""; ""HEMATOLOGICAL EFFECTS""; ""DEVELOPING CENTRAL-NERVOUS-SYSTEM TOXICITY""; ""Human Studies""; ""High-Dose Poisonings""; ""Poisoning Episode in Japan""""Poisoning Episode in Iraq""MethylmercuryToxicologyElectronic books.MethylmercuryToxicology.615.9/25663MiAaPQMiAaPQMiAaPQBOOK9910456093203321Toxicological effects of methylmercury2188852UNINA