05812nam 22007934a 450 991045591030332120200520144314.01-280-50567-29786610505678600-00-0589-X1-60129-472-7(CKB)111087028238676(EBL)267542(OCoLC)228124762(SSID)ssj0000258741(PQKBManifestationID)11204431(PQKBTitleCode)TC0000258741(PQKBWorkID)10256899(PQKB)10263034(MiAaPQ)EBC267542(Au-PeEL)EBL267542(CaPaEBR)ebr10116447(CaONFJC)MIL50567(EXLCZ)9911108702823867620020820d2002 uy 0engur|n|---|||||txtccrThiol metabolism and redox regulation of cellular functions[electronic resource] /[edited by] Alfonso Pompella, Gabor Banhegyi, Maria Wellman-RousseauAmsterdam ;Washington, DC IOS Pressc20021 online resource (365 p.)NATO science series. Series I, Life and behavioural sciences,1566-7693 ;v. 347"Published in cooperation with NATO Scientific Affairs Division.""Proceedings of the NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions, 10-13 April 2002, Pisa, Italy"--T.p. verso.0-585-45870-7 1-58603-282-8 Includes bibliographical references and index.Cover; Title page; Foreword; Preface; Contributors; Contents; Oxidative Signaling and Glutathione Synthesis; Cell Survival and Changes in Gene Expression in Cells Unable to Synthesize Glutathione; Role of Glutathione in the Regulation of Liver Metabolism; Glutathione Transport in the Endo/Sarcoplasmic Reticulum; Role of Ascorbate in Oxidative Protein Folding; Cytophotometric Investigations on Oscillating Thiol-Disulfide Equilibria and Oxidized Protein Sulfur; Protection by Pantothenic Acid against Apoptosis and Cell Damage by Oxygen Free Radicals - The Role of GlutathioneThiols as Major Determinants of the Total Antioxidant CapacityEnzymes of the Thiol-dependent Hydroperoxide Metabolism in Pathogens as Potential Drug Targets; Is there a Role of Glutathione Peroxidases in Signaling and Differentiation?; Multidrug Resistance-associated Proteins: Export Pumps for Conjugates with Glutathione, Glucuronate or Sulfate; Detoxification of Electrophilic Compounds by Glutathione S-Transferase Catalysis: Determinants of Individual Response to Chemical Carcinogens and...; Transcriptional Regulation of Glutathione S-Transferase P1-1 in Human LeukemiaMechanism of γ-Glutamyltranspeptidase Folding and Activation in the Endoplasmic ReticulumThe Role of γ-Glutamyl Transpeptidase in the Biosynthesis of Glutathione; Role of γ-Glutamyltransferase in the Homeostasis of Glutathione during Oxidative and Nitrosative Stress; The Importance of gamma-Glutamyl Transferase in Lung Glutathione Homeostasis and Antioxidant Defense; The Role of gamma-Glutamyltranspeptidase in the Metabolism and Cytotoxicity of 4-Hydroxynonenal-Glutathione Conjugate: Evidence and Hypothesis; γ-Glutamyltransferase-Dependent Prooxidant Reactions: a Factor in Multiple ProcessesSerum gamma-Glutamyl Transpeptidase: a Prognostic Marker in Cardiovascular DiseasesLipoic Acid: a Multifunctional Antioxidant; Is Glutathione an Important Neuroprotective Effector Molecule against Amyloid Beta Toxicity?; Antioxidants in Cancer Therapy: is there a Rationale to Recommend Antioxidants during Cancer Therapy?; Disulfide Exchange in CD4; Redox Regulation in Protein Folding and Chaperone Function; Reduction of the Endoplasmic Reticulum Accompanies the Oxidative Damage of Diabetes Mellitus; Analytical Developments in the Assay of Intra- and Extracellular GSH HomeostasisSignalling Potential and Protein Modifying Ability of Physiological ThiolsRedox Signaling and the Map Kinase Pathways; Redox Regulation of Mitochondrial Permeability Transition: Contrasting Effects of Lipoic Acid and its Positively Charged Analog LA-Plus; Redox State of Glutathione and Thioredoxin in Differentiation and Apoptosis; Redox Regulation of DNA Repair; Author IndexThis volume contains contributions by some of the leading scientists in the field of thiol oxidation/reduction (redox) biochemistry. It is focused on the biological/pathophysiological implications of newly-discovered functions of cellular thiols, such as glutathione in the first place.NATO science series.Series I,Life and behavioural sciences ;v. 347.AntioxidantsCongressesThiolsPhysiological effectCongressesGlutathionePhysiological effectCongressesOxidation-reduction reactionCongressesCell respirationCongressesElectronic books.AntioxidantsThiolsPhysiological effectGlutathionePhysiological effectOxidation-reduction reactionCell respiration572.7Pompella Alfonso872209Bánhegyi Gábor872210Wellman-Rousseau Maria872211NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions(2002 :Pisa, Italy)MiAaPQMiAaPQMiAaPQBOOK9910455910303321Thiol metabolism and redox regulation of cellular functions1947443UNINA