03899nam 22006374a 450 991045460330332120200520144314.00-262-28209-71-4356-9409-0(CKB)1000000000705952(EBL)3338963(SSID)ssj0000229717(PQKBManifestationID)11199515(PQKBTitleCode)TC0000229717(PQKBWorkID)10172574(PQKB)10331705(StDuBDS)EDZ0000130696(MiAaPQ)EBC3338963(OCoLC)300235040(OCoLC)503443543(OCoLC)646770521(OCoLC)694516328(OCoLC)961534620(OCoLC)962631100(OCoLC)974444433(OCoLC)974513155(OCoLC-P)300235040(MaCbMITP)7590(Au-PeEL)EBL3338963(CaPaEBR)ebr10256731(OCoLC)300235040(EXLCZ)99100000000070595220071130d2009 uy 0engur|n|---|||||txtccrProtocells[electronic resource] bridging nonliving and living matter /edited by Steen Rasmussen ... [et al.]Cambridge, Mass. MIT Pressc20091 online resource (723 p.)Description based upon print version of record.0-262-18268-8 Includes bibliographical references and index.Contents ; Preface; Acknowledgments; Introduction; I OVERVIEW: BRIDGING NONLIVING AND LIVING MATTER; 1 The Early History of Protocells: The Search for the Recipe of Life; 2 Experimental Approaches to Fabricating Artificial Cellular Life; 3 Semisynthetic Minimal Cells: New Advancements and Perspectives; 4 A Roadmap to Protocells; II INTEGRATION; 5 Steps Toward a Synthetic Protocell; 6 Assembly of a Minimal Protocell; 7 Population Analysis of Liposomes with Protein Synthesis and a Cascading Genetic Network; 8 Constructive Approach to Protocells: Theory and Experiments9 Origin of Life and Lattice Artificial Chemistry10 Models of Protocell Replication; 11 Compositional Lipid Protocells: Reproduction without Polynucleotides; 12 Evolutionary Microfluidic Complementation Toward Artificial Cells; III COMPONENTS; 13 Self-Replication and Autocatalysis; 14 Replicator Dynamics in Protocells; 15 Peptide Nucleic Acids as Prebiotic and Abiotic Genetic Material; 16 The Core of a Minimal Gene Set: Insights from Natural Reduced Genomes; 17 Parasitism and Protocells:Tragedy of the Molecular Commons18 Forming the Essential Template for Life: The Physics of Lipid Self- Assembly19 Numerical Methods for Protocell Simulations; 20 Core Metabolism as a Self-Organized System; 21 Energetics, Energy Flow, and Scaling in Life; IV BROADER CONTEXT; 22 Ganti's Chemoton Model and Life Criteria; 23 Viral Individuality and Limitations of the Life Concept; 24 Nonlinear Chemical Dynamics and the Origin of Life: The Inorganic-Physical Chemist Point of View; 25 Early Ancestors of Existing Cells; 26 Prebiotic Chemistry, the Primordial Replicator, and Modern Protocells27 Cell-like Entities: Scientific Challenges and Future Applications28 Social and Ethical Issues Concerning Protocells; Glossary; About the Authors; Index; Color PlatesThe first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory.Artificial cellsLife (Biology)Electronic books.Artificial cells.Life (Biology)576.8/3Rasmussen Steen961651MiAaPQMiAaPQMiAaPQBOOK9910454603303321Protocells2180213UNINA