04393nam 2200709 a 450 991045353760332120200520144314.03-11-080928-110.1515/9783110809282(CKB)2550000001178539(OCoLC)607788650(CaPaEBR)ebrary10588293(SSID)ssj0000559977(PQKBManifestationID)11383691(PQKBTitleCode)TC0000559977(PQKBWorkID)10568709(PQKB)10421189(MiAaPQ)EBC3040518(WaSeSS)Ind00012857(DE-B1597)41772(OCoLC)1013946755(OCoLC)840444637(DE-B1597)9783110809282(Au-PeEL)EBL3040518(CaPaEBR)ebr10588293(CaONFJC)MIL558727(OCoLC)922943346(EXLCZ)99255000000117853919960711d1997 uy 0engurcn|||||||||txtccrMammalian cell biotechnology in protein production[electronic resource] /editors, Hansjörg Hauser, Roland WagnerBerlin ;New York Walter de Gruyter19971 online resource (512 p.) Bibliographic Level Mode of Issuance: Monograph3-11-013403-9 1-306-27476-1 Includes bibliographical references and index. Frontmatter -- Preface -- Contents -- Contributors List -- 1. Genetic Manipulation of Mammalian Cells -- 1.1 Heterologous Expression of Genes in Mammalian Cells / Hauser, Hansjörg -- 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection / Schlokat, Uwe / Himmelspach, Michèle / Falkner, Falko G. / Dorner, Friedrich -- 1.3 Vectors for Gene Transfer and Expression in Animal Cells / Sandig, Volker / Lieber, Andre / Strauss, Michael -- 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells / Wurm, Florian Μ. -- 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene / Wirth, Manfred -- 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells / Schäffner, Michaela / Kaluza, Brigitte / Weidle, Ulrich Η. -- 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines / Onions, David -- 2. Biological Aspects of Animal Cells -- 2.1 Metabolic Control of Animal Cell Culture Processes / Wagner, Roland -- 2.2 Glycosylation: A Post-Translational Modification / Savage, Angela -- 3. Cell Cultivation Technology -- 3.1 Bioreactors Designed for Animal Cells / Tokashiki, Michiyuki / Yokoyama, Seiichi -- 3.2 Hydrodynamic Properties in Bioreactors / Chattopadhyay, Devamita / Garcia-Briones, Miguel / Venkat, Raghavan / Chalmers, Jeffrey J. -- 3.3 Kinetics and Simulation of Animal Cell Processes / Goergen, Jean-Louis / Marc, Annie / Engasser, Jean-Marc -- 3.4 On-line and Off-line Process Analysis / Scheper, Thomas / Freitag, Ruth / Scrienc, Friedrich -- 4. Down-Stream Processing -- 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins / Jungbauer, Alois -- 4.2 Validation of Downstream Processes / Walter, Joachim / Allgaier, Hermann -- Index -- Backmatter"Hauser and Wagner have presented the new possibilities of Mammalian Cell Biology in a very informative and stimulating manner." Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich "Hauser und Wagner haben die neuen Möglichkeiten der Mammalian Cell Biology sehr anregend dargestellt."Prof. Dr. Hans Fritz, Ludwig-Maximilians-Universität München ProteinsBiotechnologyAnimal cell biotechnologyMammalsCytologyElectronic books.ProteinsBiotechnology.Animal cell biotechnology.MammalsCytology.660/.63WF 9720rvkHauser Hansjörg1949-1038320Wagner Roland1956-1038321MiAaPQMiAaPQMiAaPQBOOK9910453537603321Mammalian cell biotechnology in protein production2459834UNINA