03303nam 2200673 450 991045349830332120200520144314.00-19-756286-80-19-933716-00-19-933715-2(CKB)2550000001181270(EBL)1602520(SSID)ssj0001080520(PQKBManifestationID)12462479(PQKBTitleCode)TC0001080520(PQKBWorkID)11071191(PQKB)10993607(MiAaPQ)EBC1602520(StDuBDS)EDZ0002341517(Au-PeEL)EBL1602520(CaPaEBR)ebr10826259(CaONFJC)MIL561296(OCoLC)868264144(EXLCZ)99255000000118127020140124h20142014 uy 0engur|n|---|||||txtccrHallelujah moments tales of drug discovery /Eugene H. CordesNew York, New York :Oxford University Press,2014.©20141 online resource (258 p.)Oxford scholarship onlineIncludes index.0-19-933714-4 1-306-30045-2 Includes bibliographical references and index.Cover; Contents; Preface; Acknowledgments; 1. Seduced by Drug Discovery; 2. The Small Molecules of Life; 3. Proteins: Molecular Wonders in Three Dimensions; 4. Proteins Perform Multiple Functions: Enzymes, Receptors, Ion Channel Proteins; 5. Drug Discovery and Development: The Road from an Idea to Promoting Human Health; 6. Finasteride: The Gary and Jerry Show; 7. Basic Research, Snake Venoms, and ACE Inhibitors: Ondetti, Cushman, and Patchett; 8. Statins: Protection Against Heart Attacks and Strokes-Hallelujah!; 9. Th e Perils of Primaxin; 10. Avermectins: Molecules of Life Battle Parasites11. Fludalanine: Nice Try But No Hallelujah12. Diabetes Breakthroughs: Januvia and Janumet; NOTES; INDEX; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; ZPharmeceutical drug discovery has wide-reaching and obvious effects on the lives of people everywhere, and yet the general public knows very little about the way in which these important products are conceived. We rely on pharmaceuticals to keep us healthy in countless ways, with almost no understanding of the process behind the creation of the drugs we use. In this book, Eugene Cordes reveals just how some of the most important and influential drugs are made. He shares his firsthand knowledge of the drug-discovery world, having spent a long and distinguished career on both the academic and industrial side of pharmaceutical research.Oxford scholarship online.Drug developmentHistoryDrugsResearchPharmaceutical chemistryElectronic books.Drug developmentHistory.DrugsResearch.Pharmaceutical chemistry.615.19Cordes Eugene H296633MiAaPQMiAaPQMiAaPQBOOK9910453498303321Hallelujah moments2265275UNINA