05654nam 2200721 450 991045338070332120200520144314.01-4557-7676-9(CKB)2550000001168884(EBL)1576657(OCoLC)865334317(SSID)ssj0001141550(PQKBManifestationID)11631429(PQKBTitleCode)TC0001141550(PQKBWorkID)11090656(PQKB)10627651(MiAaPQ)EBC1576657(Au-PeEL)EBL1576657(CaPaEBR)ebr10817782(CaONFJC)MIL550170(EXLCZ)99255000000116888420131230d2014 uy 0engurcnu||||||||txtccrMolecular sensors and nanodevices principles, designs and applications in biomedical engineering /John X. J. Zhang, Kazunori HoshinoWaltham, Massachusetts ;Oxford, England :William Andrew,2014.©20141 online resource (512 p.)Micro & Nano Technologies SeriesDescription based upon print version of record.1-4557-7631-9 1-306-18919-5 Includes bibliographical references at the end of each chapters and index.Front Cover; Molecular Sensors and Nanodevices; Copyright Page; Contents; About the Authors; Preface; Acknowledgement; 1 Introduction to Molecular Sensors; 1.1 Introduction; 1.2 Principles of Molecular Sensors; 1.2.1 Definition of Molecular Sensors; Capture and Recognition; Transduction; Measurement and Analysis; 1.2.2 Applications of Molecular Sensors; 1.2.3 Model of a Molecular Sensor; Capture and Recognition; Transduction; Measurement and Analysis; 1.2.4 Example of Molecular Sensor 1: Immunosensor Based on Field Effect Transistor; Capture and Recognition Elements; TransducerMeasurement and Analysis 1.2.5 Example of Molecular Sensor 2: Animal Olfactory System; 1.3 Capture and Recognition Elements in Molecular Sensors; 1.3.1 Antibody-Antigen Binding; Antibody Overview; Antibody-Antigen Binding; Immunoassays; 1.3.2 DNA as a Recognition Element; Discovery of DNA; DNA Structure and Characteristics; RNA Function; DNA Hybridization; Oligonucleotides; Nucleic Acid Sensors; 1.3.3 Aptamers; Aptamer Selection Process; Example Process: Bead Based Selection; 1.4 Transduction Mechanisms; 1.4.1 Electrical Transduction; Optical Transduction; Mechanical Transduction1.4.2 Sensitivity of a Transducer Responsivity; Noise in a Sensing System; Sensitivity; Thermal Noise; Example 1; Example 2; Example 3; 1.5 Performance of Molecular Sensors; 1.6 Animals as Molecular Sensors; 1.6.1 Sensitivity of Animal Olfactory Systems; Canine Olfactory System; Insect Olfactory System; 1.6.2 Applications of Animal Molecular Sensors; Explosive Detection; Canine Detection of Explosives; Pouched Rats for the Detection of Landmines; Honeybees for the Detection of Landmines; Disease Detection; Canines for Cancer Detection; Pouched Rats for the Detection of TuberculosisOther Applications Canine Detection of Pirated DVDs; Canine Detection of Bed Bugs; 1.6.3 Discussion on Animals as Molecular Sensors; 1.7 Conclusion; Problems; P1.1 Molecular Sensor; P1.2 Molecular Sensor; P1.3 Recognition Element; P1.4 Basics of Molecular Sensing; P1.5 Antibodies; P1.6 Immunosensing; P1.7 DNA Biosensor; P1.8 DNA Basics; P1.9 DNA Basics; P1.10 DNA Basics; P1.11 DNA Basics; P1.12 Thermal Noise; P1.13 Thermal Noise, Responsivity and Sensitivity; P1.14 Sensitivity of a Force Sensor; P1.15 Animals as Molecular Sensors; References; Further Reading2 Fundamentals of Nano/Microfabrication and Effect of Scaling 2.1 Introduction; 2.2 Scaling in Molecular Sensors; 2.3 Microfabrication Basics; 2.3.1 Silicon as a Material for Microfabrication; Silicon Crystal Structure; 2.3.2 Photolithography; Process of Photolithography; Resolution of Photolithography; Contact and Proximity Exposure; Projection Exposure; 2.3.3 Deposition; Spin Coating; Thermal Oxidation; Evaporation; E-beam Evaporation; Resistive Heat (Joule Heat) Evaporation; Problems Associated with Evaporation; Sputtering; Chemical Vapor Deposition; Polysilicon; Amorphous siliconSilicon DioxideWith applications ranging from medical diagnostics to environmental monitoring, molecular sensors (also known as biosensors, chemical sensors, or chemosensors), along with emerging nanotechnologies offer not only valuable tools but also unlimited possibilities for engineers and scientists to explore the world. New generation of functional microsystems can be designed to provide a variety of small scale sensing, imaging and manipulation techniques to the fundamental building blocks of materials. This book provides comprehensive coverage of the current and emerging technologies of molecular sensMicro & nano technologies.BiosensorsDetectorsNanoelectronicsNanostructured materialsElectric propertiesElectronic books.Biosensors.Detectors.Nanoelectronics.Nanostructured materialsElectric properties.610.28Zhang John X. J948331Hoshino Kazunori948332MiAaPQMiAaPQMiAaPQBOOK9910453380703321Molecular sensors and nanodevices2143408UNINA01419nam 2200337 n 450 99638722880331620221108054435.0(CKB)1000000000621879(EEBO)2240872544(UnM)99858856(EXLCZ)99100000000062187919850502d1653 uy |engurbn#|||a|bb|Moses and Aaron, or The types and shadovvs of our Saviour in the old Testament. Opened and explained, by T. Taylor D. D. Very usefull for the better understanding the whole Scripture[electronic resource]London, Printed for John Williams, at the Crown in St. Pauls Church-yard1653[16], 129, 128-309, [1] p"The epistle dedicatorie" and "To the Christian reader" signed: William Jemmat.Annotation on Thomason copy: "May 13th".Reproduction of the original in the British Library.eebo-0018Taylor Thomas1576-1632.845959Jemmat William1596?-1678.1003922Cu-RivESCu-RivESCStRLINWaOLNBOOK996387228803316Moses and Aaron, or The types and shadovvs of our Saviour in the old Testament. Opened and explained, by T. Taylor D. D. Very usefull for the better understanding the whole Scripture2305440UNISA