04621nam 2200625Ia 450 991045290300332120200520144314.01-61942-455-X(CKB)2550000001040563(EBL)3017654(SSID)ssj0000826844(PQKBManifestationID)12407503(PQKBTitleCode)TC0000826844(PQKBWorkID)10809291(PQKB)11123435(MiAaPQ)EBC3017654(Au-PeEL)EBL3017654(CaPaEBR)ebr10654625(OCoLC)923652879(EXLCZ)99255000000104056320110329d2012 uy 0engur|n|---|||||txtccrDNA replication and mutation[electronic resource] /Raymond P. Leitner, editorHauppauge, NY Nova Science20121 online resource (204 p.)DNA and RNADescription based upon print version of record.1-61324-490-8 Includes bibliographical references (p. 158-177) and index.""DNA REPLICATIONAND MUTATION""; ""DNA AND RNA: PROPERTIESAND MODIFICATIONS, FUNCTIONSAND INTERACTIONS, RECOMBINATIONAND APPLICATIONS""; ""Library of Congress Cataloging-in-Publication Data""; ""Contents""; ""Preface""; ""Connections between BLMand the Fanconi AnemiaPathway in the Repair ofReplication Fork Damage""; ""Abstract""; ""RecQ DNA Helicases""; ""BLM and Regulationof Homologous Replication""; ""Connections between FANCM of the FanconiAnemia Pathway and BLM""; ""Connections between FANCJ of the FAPathway and BLM""""The Structure-Specific EndonucleaseSLX4-SLX1 and Its Relationshipto BLM and the FA Pathway""""Conclusion""; ""Acknowledgments""; ""References""; ""Mutagenic Potentialof Methacrylates Usedin Restorative Dentistry""; ""Abstract""; ""Introduction""; ""Materials and Methods""; ""Chemicals""; ""Cells""; ""Cell Treatment""; ""Cell Viability""; ""Plasmid Relaxation Assay""; ""Comet Assay""; ""Oxidative Damage to DNA""; ""DNA Double-Strand Breaks Assays""; ""Apoptosis""; ""Cell Cycle""; ""Data Analysis""; ""Results""; ""Cell Viability""; ""DNA Damage In Vitro""""DNA Damage in Human Gingival Fibroblasts""""DNA Double-Strand Breaks""; ""DNA Repair""; ""Oxidative Modifications to the DNA Bases""; ""Apoptosis""; ""Cell Cycle""; ""Discussion""; ""Acknowledgments""; ""Conflict of Interest Statement""; ""References""; ""DNA Mutation of theProgranulin (GRN) Gene inFamilial Frontotemporal LobarDegeneration (FTLD): A Studyof the Pathology of Nine Cases""; ""Abstract""; ""Introduction""; ""Heterogeneity of FTLD-TDP""; ""DNA Mutations""; ""Objectives""; ""Materials and Methods""; ""Cases""; ""Histological Methods""; ""Morphometric Measurements""""Measurement of Density of Inclusions""""Spatial Patterns of the Inclusions""; ""Laminar Distribution""; ""Density of TDP-43Immunoreactive Inclusions""; ""Spatial Patterns of TDP-43Immunoreactive Inclusions""; ""Laminar Distribution of TDP-43Immunoreactive Inclusions""; ""Conclusion""; ""Acknowledgments""; ""References""; ""Effect of a Specific MammalianDNA Polymerase α-Inhibitor,Dehydroaltenusin, on DNAReplication in Cultured Cells""; ""Abstract""; ""Abbreviations""; ""1. Introduction""; ""2. Production and Isolationof Dehydroaltenusin""""3. Effect of Dehydroaltenusin on Polsand other DNA Metabolic Enzymes""""4. Mode of Pol α Inhibitionby Dehydroaltenusin""; ""5. Effect of Dehydroaltenusinon Human Cancer Cell Growth""; ""6. Inhibitory Properties of ehydroaltenusinon Human Cancer Cell Growth""; ""7. Effect of Dehydroaltenusin on DNAReplication in NIH3T3 Cells""; ""8. Discussion""; ""Conclusion""; ""Acknowledgments""; ""References""; ""Gel-Based Methods Using DNABindingZinc(II) Complexesfor the Detectionof DNA Mutations""; ""Abstract""; ""Introduction""; ""Zinc(II)�Cyclen""""Zinc(II)�Cyclen PolyacrylamideGel Electrophoresis""DNA and RNA : Properties and Modifications, Functions and Interactions, Recombination and ApplicationsDNA replicationDNASynthesisElectronic books.DNA replication.DNASynthesis.572.8/645572.8/645Leitner Raymond P937745MiAaPQMiAaPQMiAaPQBOOK9910452903003321DNA replication and mutation2112414UNINA