05035nam 2200613Ia 450 991045181150332120200520144314.0(CKB)1000000000450753(EBL)3377538(SSID)ssj0000169503(PQKBManifestationID)11164581(PQKBTitleCode)TC0000169503(PQKBWorkID)10203911(PQKB)11149449(MiAaPQ)EBC3377538(Au-PeEL)EBL3377538(CaPaEBR)ebr10071627(OCoLC)923271186(EXLCZ)99100000000045075320050324d1994 uy 0engur|n|---|||||txtccrHealth effects of Permethrin-impregnated Army battle-dress uniforms[electronic resource] /Subcommittee to Review Permethrin Toxicity from Military Uniforms, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research CouncilWashington, DC National Academy Press19941 online resource (154 p.)Project was supported by the U.S. Army.Subcommittee chairman: Ernest Eugene McConnell.0-309-57300-9 Includes bibliographical references.""Health Effects of Permethrin Impregnated Army Battle-Dress Uniforms""; ""Copyright""; ""Preface""; ""Contents""; ""Summary""; ""EXPOSURE ASSESSMENT""; ""PHARMACOKINETICS""; ""ACUTE TOXICITY""; ""SUBCHRONIC TOXICITY""; ""DERMAL TOXICITY""; ""OCULAR TOXICITY""; ""NEUROTOXICITY""; ""LIVER TOXICITY""; ""IMMUNOTOXICITY""; ""REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""GENOTOXICITY""; ""CARCINOGENICITY""; ""CONCLUSIONS""; ""1 Introduction""; ""2 Exposure Assessment""; ""MILITARY NONFIELD PERSONNEL""; ""MILITARY FIELD PERSONNEL""; ""GARMENT WORKERS""; ""RECOMMENDATIONS""""3 Pharmacokinetics of Permethrin""""ABSORPTION OF PERMETHRIN""; ""Oral Absorption""; ""Dermal Absorption""; ""Absorption in Humans""; ""Absorption in Animals""; ""INTERACTIONS""; ""METABOLISM""; ""HYDROLYSIS""; ""OXIDATION""; ""RELATIONSHIP TO TOXICITY""; ""ELIMINATION""; ""DISTRIBUTION""; ""Tissue Concentrations""; ""Protein Binding""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""4 Acute and Short-Term Toxicity of Permethrin""; ""ACUTE TOXICITY""; ""Human Studies""; ""Animal Studies""; ""SUBACUTE AND SUBCHRONIC TOXICITY""; ""Oral Exposure""; ""Mouse""; ""Rat""; ""Dog""; ""Rabbit""""Cow""""Dermal Exposure""; ""Inhalation Exposure""; ""CONCLUSIONS""; ""5 Dermal and Ocular Toxicity of Permethrin""; ""DERMAL TOXICITY""; ""Human Data""; ""Clinical Trials""; ""Animal Data""; ""Acute and Subchronic Effects""; ""Photochemical Irritation""; ""OCULAR TOXICITY""; ""CONCLUSIONS""; ""Ocular Toxicity""; ""Dermal Toxicity""; ""Recommendation""; ""6 Neurotoxicity of Permethrin""; ""HUMAN DATA""; ""ANIMAL DATA""; ""Neurotoxic Effects""; ""Rats""; ""Hens""; ""Neurobehavioral Effects""; ""CONCLUSIONS""; ""RECOMMENDATIONS""; ""7 Liver and Other Organ Toxicity of Permethrin""""LIVER TOXICITY""""Human Data""; ""Animal Data""; ""OTHER ORGAN TOXICITY""; ""Human Data""; ""Animal Data""; ""CONCLUSIONS""; ""8 Immunotoxicity of Permethrin""; ""CONCLUSIONS""; ""RECOMMENDATIONS""; ""9 Reproductive and Developmental Toxicity Of Permethrin""; ""RAT STUDIES""; ""MOUSE STUDIES""; ""RABBIT STUDIES""; ""OTHER STUDIES""; ""CONCLUSIONS""; ""10 Genotoxicity of Permethrin""; ""GENE MUTATIONS""; ""CHROMOSOMAL EFFECTS""; ""OTHER GENOTOXIC EFFECTS""; ""CONCLUSIONS""; ""11 Carcinogenicity of Permethrin""; ""CARCINOGENICITY STUDIES IN MICE""; ""ICI Mouse Study""; ""FMC Mouse Studies""""Burroughs Wellcome Mouse Study""""CARCINOGENICITY STUDIES IN RATS""; ""ICI Rat Study""; ""FMC Rat Study""; ""Burroughs Wellcome Rat Study""; ""TUMOR PROMOTION STUDIES: SHIMKIN MOUSE LUNG BIOASSAY""; ""CONCLUSIONS""; ""CARCINOGENICITY RISK ASSESSMENT""; ""Hazard Identification""; ""Dose-Response Assessment""; ""Risk Characterization""; ""Military Nonfield Personnel""; ""Military Field Personnel""; ""Garment Workers""; ""Conclusions""; ""12 Summary of Recommendations""; ""EXPOSURE ASSESSMENT""; ""PHARMACOKINETICS""; ""DERMAL TOXICITY""; ""NEUROTOXICITY""; ""IMMUNOTOXICITY""; ""GENOTOXICITY""""References""PyrethroidsToxicologyMilitary uniformsElectronic books.PyrethroidsToxicology.Military uniforms.615.902McConnell Ernest E874793National Research Council (U.S.).Board on Environmental Studies and Toxicology.National Research Council (U.S.).Commission on Life Sciences.MiAaPQMiAaPQMiAaPQBOOK9910451811503321Health effects of Permethrin-impregnated Army battle-dress uniforms1953049UNINA