03414nam 2200673 a 450 991045172290332120200520144314.03-540-78899-910.1007/978-3-540-78899-7(CKB)1000000000492376(EBL)364077(OCoLC)288467972(SSID)ssj0000152786(PQKBManifestationID)11163183(PQKBTitleCode)TC0000152786(PQKBWorkID)10339956(PQKB)10392832(DE-He213)978-3-540-78899-7(MiAaPQ)EBC364077(PPN)12906226X(Au-PeEL)EBL364077(CaPaEBR)ebr10253708(EXLCZ)99100000000049237620090129d2008 uy 0engur|n|---|||||txtrdacontentcrdamediacrrdacarrierFacilitative glucose transporters in articular chondrocytes[electronic resource] expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines /Ali Mobasheri ... [et al.]1st ed. 2008.Berlin Springer20081 online resource (95 pages)Advances in anatomy, embryology, and cell biology,0301-5556 ;200Description based upon print version of record.3-540-78898-0 Includes bibliographical references and index.Articular Cartilage: Structure, Function, and Pathophysiology -- Does Arthritis Have a Nutritional Etiology? -- Metabolic Dysfunction in Arthritis -- Glucose: An Essential Metabolite and Structural Precursor for Articular Cartilage -- Mammalian Sugar Transporter Families: GLUT and SGLT -- Molecular Diversity of Facilitative Glucose Transporters in Articular Chondrocytes -- Regulation of Glucose Transport by Nonsteroidal Anti-inflammatory Drugs -- Glucose Transporters in the Intervertebral Disc -- Glucose Transporter Expression and Regulation in Embryonic and Mesenchymal Stem Cells -- Concluding Remarks.Articular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchymal cell differentiation, chondrogenesis and skeletal morphogenesis. Glucose is an important metabolic fuel for differentiated chondrocytes during post-natal development and in adult articular cartilage and is a common structural precursor for the synthesis of extracellular matrix glycosaminoglycans.Advances in anatomy, embryology, and cell biology ;v. 200.GlucoseArticular cartilageCartilage cellsCytokinesElectronic books.Glucose.Articular cartilage.Cartilage cells.Cytokines.612.75613.283Mobasheri A(Ali)862811MiAaPQMiAaPQMiAaPQBOOK9910451722903321Facilitative glucose transporters in articular chondrocytes1926177UNINA