04470nam 22006374a 450 991045166290332120200520144314.01-281-97519-297866119751971-934559-87-3(CKB)1000000000481748(EBL)322479(OCoLC)335627674(SSID)ssj0000218142(PQKBManifestationID)11181563(PQKBTitleCode)TC0000218142(PQKBWorkID)10213318(PQKB)10622574(MiAaPQ)EBC322479(Au-PeEL)EBL322479(CaPaEBR)ebr10210545(CaONFJC)MIL197519(OCoLC)191726483(EXLCZ)99100000000048174820070806d2008 uy 0engur|n|---|||||txtccrParkinson's disease[electronic resource] diagnosis and clinical management /edited by Stewart A. Factor, William J. Weiner2nd ed., rev. and updated.New York Demosc20081 online resource (858 p.)Description based upon print version of record.1-933864-99-0 1-933864-00-1 Includes bibliographical references and index.Cover; Title Page; Table of Contents; Foreword; Preface; Acknowledgments; Contributors; 1. James Parkinson: The Man and the Essay; 2. Paralysis Agitans in the Nineteenth Century; 3. Charcot and Parkinson's Disease; 4. Timeline of Parkinson's Disease History Since 1900; 5. Epidemiology; 6. Cardinal Features of Early Parkinson's Disease; 7. Gait Disturbances; 8. Sensory Symptoms; 9. Voice, Speech, and Swallowing Disorders; 10. Gastrointestinal Features; 11. Autonomic Dysfunction; 12. Sleep Disorders; 13. Natural History; 14. Clinical Rating Scales; 15. Dementia; 16. Depression17. Anxiety and Panic18. Apathy and Amotivation; 19. Impulse-control Disorders; 20. Neuropathology; 21. Neurochemistry; 22. Basal Ganglia: Anatomy and Physiology; 23. Dopamine Receptor Diversity; 24. Status of Biological Markers; 25. Positron Emission Tomography; 26. Single Photon Emission Computed Tomography; 27. Magnetic Resonance Imaging; 28. Controversies in Neuroimaging; 29. Animal Models; 30. Pathogenesis: Oxidative Stress, Mitochondrial Dysfunction, and Excitotoxicity; 31. The Concept and Mechanisms of Programmed Cell Death; 32. Protein Aggregation33. Etiology: The Role of Environment and Genetics34. The Impact of MPTP on Parkinson's Disease Research: Past, Present, and Future; 35. Rotenone and Other Toxins; 36. Inflammation; 37. Genetics; 38. Levodopa: A Pharmacologic Miracle Four Decades Later; 39. Amantadine and Anticholinergics; 40. Monoamine Oxidase Inhibitors; 41. Dopamine Agonists; 42. Catechol-O-Methyltransferase Inhibitors; 43. Excitatory Amino Acid Antagonists; 44. Adenosine A2A Receptor Antagonists; 45. Complementary and Alternative Medicine; 46. Motor Fluctuations and Dyskinesia; 47. Fluctuations of Nonmotor Symptoms48. Psychosis and Other Behaviors49. Treatment of Dementia; 50. Status of Neuroprotective Therapies; 51. Symptomatic Treatment Approaches for Early Parkinson's Disease; 52. Progress in Gene Therapy; 53. Genetic Testing; 54. Deep Brain Stimulation; 55. Neural Transplantation: Yesterday, Today, and Tomorrow; 56. Stereotactic Pallidotomy and Thalamotomy; 57. Parkinson's-plus Disorders; 58. Symptomatic Parkinsonism; 59. Outcome Measures; 60. Family Caregiving; 61. Economics; 62. Driving; 63. The Patient's Perspective; IndexParkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease.Parkinson's diseaseElectronic books.Parkinson's disease.616.8/33Factor Stewart A.1956-990788Weiner William J316108MiAaPQMiAaPQMiAaPQBOOK9910451662903321Parkinson's disease2485843UNINA