00792nam0-22002771i-450-9900011166104033210-7923-2153-7000111661FED01000111661(Aleph)000111661FED01000111661--------d--------km-y0itay50------baeng<<The >>Context of ExplanationMartin BunzlDordrecht (NL)Kluwer1993Boston studies in the philosophy of science149Fondamenti delle scienze fisiche e naturali501Bunzl,Martin53524ITUNINARICAUNIMARCBK9900011166104033214-012.14819305FI1FI1Context of Explanation337422UNINA03640nam 22006732 450 991045040480332120151005020622.01-107-12776-91-280-41736-697866104173601-139-14566-50-511-18051-90-511-06598-10-511-05967-10-511-30742-X0-511-54644-00-511-06811-5(CKB)1000000000017937(EBL)217832(OCoLC)228111013(SSID)ssj0000120648(PQKBManifestationID)11145893(PQKBTitleCode)TC0000120648(PQKBWorkID)10092557(PQKB)10522231(UkCbUP)CR9780511546440(MiAaPQ)EBC217832(Au-PeEL)EBL217832(CaPaEBR)ebr10069982(CaONFJC)MIL41736(EXLCZ)99100000000001793720090508d2002|||| uy| 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierChemotherapeutic targets in parasites contemporary strategies /Tag E. Mansour ; with the assistance of Joan MacKinnon Mansour[electronic resource]Cambridge :Cambridge University Press,2002.1 online resource (xiv, 226 pages) digital, PDF file(s)Title from publisher's bibliographic system (viewed on 05 Oct 2015).0-521-01836-6 0-521-62065-1 Includes bibliographical references and index.Cover; Half-title; Title; Copyright; Contents; Preface; Acknowledgments; 1 The Search for Antiparasitic Agents; 2 Biophysical, Genomic, and Proteomic Analysis of Drug Targets; 3 Energy Metabolism in Parasitic Helminths; 4 Antimalarial Agents and Their Targets; 5 Antitrypanosomal and Antileishmanial Targets; 6 Targets in Amitochondrial Protists; 7 Neuromuscular Structures and Microtubules as Targets; 8 Targets in the Tegument of Flatworms; Epilogue; IndexParasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry.Antiparasitic agentsParasitic diseasesChemotherapyAntiparasitic agents.Parasitic diseasesChemotherapy.616.9/6061Mansour Tag E.1047680Mansour Joan MacKinnonUkCbUPUkCbUPBOOK9910450404803321Chemotherapeutic targets in parasites2475413UNINA03726nam 22006615 450 991039274960332120250610110206.09783030417611303041761110.1007/978-3-030-41761-1(CKB)4100000011040242(MiAaPQ)EBC6177173(DE-He213)978-3-030-41761-1(PPN)257147829(Perlego)3481724(MiAaPQ)EBC6177234(MiAaPQ)EBC29090468(EXLCZ)99410000001104024220200416d2020 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierImmigration Policy and Right-Wing Populism in Western Europe /by Anna McKeever1st ed. 2020.Cham :Springer International Publishing :Imprint: Palgrave Macmillan,2020.1 online resource (xv, 168 pages) illustrations9783030417604 3030417603 Chapter 1 Introduction -- Chapter 2 Explaining causes and dynamics of policy change and policy deadlock -- Chapter 3 From detoxification strategy back to 'nasty party': explaining the Conservative's turn on immigration between 2005 and 2015 -- Chapter 4 Immigration policy and the SVP: resisting the EU and fighting Switzerland's so-called 'Islamisation' -- Chapter 5 Immigration during Sarkozy's time in office: economic orientation and cultural backlash -- Chapter 6 Explaining the variation in conservative parties' responses to immigration -- Chapter 7 Conclusion.Immigration has become one of the central issues dominating the agenda of political parties, and has also played a crucial role in the rise of right-wing populism in Western Europe. This book explores the role of conservative parties in immigration policy change. The following questions are addressed: What explains the introduction of restrictive immigration policies across a number of European states? Why do conservative parties choose to toughen their immigration policy stances? How can we explain the variation in the factors that affect conservative parties' immigration policy-making logics? What mechanisms account for the dynamics of immigration policy change or policy deadlock? Based on interviews with political elites and policy makers in the UK, Switzerland and France, the book explains why governmental conservative parties in these countries revised their immigration policy stances and steered immigration policy in a more restrictive direction between 2002 and 2015. Anna McKeever is Lecturer in Social Sciences at the University of the West of Scotland, UK. Her research interests include party politics, immigration and populism.EuropePolitics and governmentPolitical planningEmigration and immigrationPolitical scienceEuropean PoliticsPublic PolicyHuman MigrationPolitical ScienceEuropePolitics and government.Political planning.Emigration and immigration.Political science.European Politics.Public Policy.Human Migration.Political Science.320.5662094320McKeever Annaauthttp://id.loc.gov/vocabulary/relators/aut1064462MiAaPQMiAaPQMiAaPQBOOK9910392749603321Immigration Policy and Right-Wing Populism in Western Europe2538372UNINA