04124nam 2200697Ia 450 991045036770332120200520144314.01-280-50485-497866105048551-4294-0199-01-60750-118-X600-00-0430-31-60129-099-3(CKB)1000000000243918(EBL)265938(OCoLC)191037887(SSID)ssj0000158115(PQKBManifestationID)11162915(PQKBTitleCode)TC0000158115(PQKBWorkID)10141746(PQKB)11339851(MiAaPQ)EBC265938(PPN)164991336(Au-PeEL)EBL265938(CaPaEBR)ebr10130668(CaONFJC)MIL50485(OCoLC)71368352(EXLCZ)99100000000024391820050805d2005 uy 0engur|n|---|||||txtccrFree radicals and diseases[electronic resource] gene expression, cellular metabolism and pathophysiology /edited by Tilman GruneAmsterdam ;Oxford IOS Pressc20051 online resource (204 p.)NATO science series. Series I, Life and behavioural sciences,1566-7693 ;v. 367Description based upon print version of record.1-58603-518-5 Includes bibliographical references and index.Title page; Preface; Contents; DNA Lesions as Biomarkers of Inflammation and Oxidative Stress: A Preliminary Evaluation; Lipid Peroxidation Measurements - Methodological Approaches and Clinical Importance; Role of Oxidative Stress in Aging of the Yeast Saccharomyces cerevisiae; mtNOS: Regulation by Mitochondrial Membrane Potential; Mutliplicity of Mitochondrial Functioning; ROS-Induced Oscillations of Mitochondrial Transmembrane Potential in Cultured Rat Astocytes; The Effects of Nitric Oxide and Peroxynitrite on MnSOD (E. coli)The Proteasomal Degradation System and Its Role During Oxidative StressPeptide Methionine Sulfoxide Reductases in Aging and Oxidative Stress; Activation of Microglial Proteolysis; Vitamin E Metabolism; Significance of the alpha-Tocopherol Salvage Pathway; Induction and Inhibition of Apoptotic Pathways by Hydrogen Peroxide; Photooxidative Processes in Skin: From Damage to Signaling; Role of Cholesterol or Homocysteine in the Development of Atherosclerosis: Effect of Vitamin E; Different Roles of Nitric Oxide in Regulation of Interscapular Brown Adipose Tissue HyperplasiaAdaptation to Exercise-Induced Oxidative StressClinical Use of Carotenoids - Antioxidative Protection versus Prooxidative Side Effects; Author IndexThis publication contains an extensive overview of free radicals and diseases, including both basic science approaches and clinical applications. The research of the last decades has contributed substantially to the understanding role and function of these metabolites. It is the aim of the editors to include a large variety of biological models ranging from yeast over mitochondria, isolated cells and cell culture models to animals and humans. The topics discussed focus on the function and integrity of mitochondria under oxidative conditions, the role of protein oxidation and proteolysis in theNATO science series.Series I,Life and behavioural sciences ;v. 367.Free radicals (Chemistry)PathophysiologyActive oxygenPathophysiologyElectronic books.Free radicals (Chemistry)Pathophysiology.Active oxygenPathophysiology.616.07Grune Tilman914277NATO Advanced Study Institute on Free Radicals and Diseases: Gene Expression, Cellular Metabolism and PathophysiologyMiAaPQMiAaPQMiAaPQBOOK9910450367703321Free radicals and diseases2136087UNINA