02674nam 2200649 450 991045026540332120200520144314.01-280-50204-597866105020420-19-512593-20-19-802911-X0-19-534839-71-60256-775-1(CKB)1000000000245636(EBL)279515(OCoLC)476022870(SSID)ssj0000199862(PQKBManifestationID)11171801(PQKBTitleCode)TC0000199862(PQKBWorkID)10197017(PQKB)10369313(MiAaPQ)EBC4701929(MiAaPQ)EBC279515(Au-PeEL)EBL4701929(CaPaEBR)ebr11273339(OCoLC)60932736(EXLCZ)99100000000024563620161012h19991999 uy 0engur|n|---|||||txtccrA means to an end the biological basis of aging and death /William R. ClarkNew York ;Oxford, [England] :Oxford University Press,1999.©19991 online resource (252 p.)Originally published: 1999.0-19-512593-2 0-19-515375-8 Includes bibliographical references and index.Contents; Acknowledgments; Introduction; 1. Aging, Senescence, and Lifespan; 2. The Nature of Cellular Senescence and Death; 3. The Evolution of Senescence and Death; 4. Of Embryos and Worms and Very Old Men: The Developmental Genetics of Senescence and Lifespan; 5. Human Genetic Diseases That Mimic the Aging Process; 6. Cycling to Senescence; 7. Replicative Immortality: Cancer and Aging; 8. Caloric Restriction and Maximum Lifespan; 9. With Every Breath We Take: Oxidative Stress and Cellular Senescence; 10. The Aging Brain; 11. A Conditional Benefit; Bibliography; IndexIn this work, the various theories of ageing are explained and assessed. The author presents case accounts about disorders that open windows on to the ageing process. The impacts of ageing on the brain and nervous system are given special attention, as are the effects of caloric restriction on maximum lifespan.CellsAgingApoptosisElectronic books.CellsAging.Apoptosis.612.6/7Clark William R.1938-262163MiAaPQMiAaPQMiAaPQBOOK9910450265403321A means to an end2154661UNINA