04553nam 2201273z- 450 991055743700332120231214133040.0(CKB)5400000000043353(oapen)https://directory.doabooks.org/handle/20.500.12854/69362(EXLCZ)99540000000004335320202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierRadiopharmaceuticals for PET Imaging - Issue ABasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (212 p.)3-03943-242-7 3-03943-243-5 Positron emission tomography (PET) is a very useful technique for medical diagnosis and drug development. Radiopharmaceuticals are a key element in PET techniques and one of the pivotal factors influencing the applications of PET. The aim of this Special Issue of Molecules is to report on the recent research work on a number of aspects of PET radiopharmaceuticals and their preclinical and clinical use. More specifically, the content of this Special Issue includes but is not limited to radiolabeling design, radiosynthesis, synthesis techniques, quality control methodologies, GMP production methods, product formulation, in vitro and in vivo preclinical PET evaluations, clinical evaluations, dosimetry, stability study and metabolite analysis, and modeling.Medicinebicssckinetic analysisSiglec-9gallium-68vascular adhesion proteinVAP-1infectioninflammationosteomyelitisanimal modelStaphylococcus aureusmultiple myelomapositron emission tomography/computed tomographyradiopharmaceuticals18F-fluorodeoxyglucosetetrazine ligationPETSPECTindium-11fluorine-18positron emission tomography (PET), defluorinationisotopic exchangesilicon-based fluoride acceptorbioorthogonal chemistrytetrazineinverse electron-demand Diels-Alder ligationopioidnaloxoneoverdosefentanylcarfentanil[11C]carfentanilpositron emission tomographyreceptor occupancypharmacokinetics[18F]AlFNOTANODAGAPODSthiol-reactivelinkeraffibody moleculebioconjugationEGFRtumor imagingvulnerable plaquemolecular imagingPET imagingnanobodysingle-domain antibodysub-millimetre resolutionAlF-radiolabellingpreclinical radiopharmaceutical dosimetryimage-based internal dosimetryOLINDAMCT1/MCT4 lactate transporter inhibitor[18F]FACHradiation safetysigma-1 receptor availabilityorthotopic xenograft of glioblastoma in mousesmall animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI)(S)-(−)-[18F]fluspidineimaging-based biomarkerSV2A proteinPET radiotracerssynaptic lossradiochemistrypreclinical developmentclinical outcomesmonocarboxylate transporters (MCTs)FACH18F-labeled analog of FACHα-CCAblood-brain barrier (BBB)positron emission tomography (PET) imagingpeptidesproteolysismetabolic stabilityMedicineRoivainen Anneedt1323768Li Xiang-GuoedtRoivainen AnneothLi Xiang-GuoothBOOK9910557437003321Radiopharmaceuticals for PET Imaging - Issue A3035833UNINA04630nam 22008175 450 991043822690332120200919224504.03-642-40555-X10.1007/978-3-642-40555-6(CKB)3710000000031278(EBL)1591967(SSID)ssj0001067123(PQKBManifestationID)11944692(PQKBTitleCode)TC0001067123(PQKBWorkID)11079524(PQKB)10612295(DE-He213)978-3-642-40555-6(MiAaPQ)EBC1591967(iGPub)SPNA0028491(PPN)176114912(EXLCZ)99371000000003127820131127d2013 u| 0engur|n|---|||||txtccrAdvance Care Decision Making in Germany and Italy A Comparative, European and International Law Perspective /edited by Stefania Negri, Jochen Taupitz, Amina Salkić, Anna Zwick1st ed. 2013.Berlin, Heidelberg :Springer Berlin Heidelberg :Imprint: Springer,2013.1 online resource (281 p.)Veröffentlichungen des Instituts für Deutsches, Europäisches und Internationales Medizinrecht, Gesundheitsrecht und Bioethik der Universitäten Heidelberg und Mannheim,1617-1497 ;41Description based upon print version of record.3-642-40554-1 Includes bibliographical references.Foreword -- Universal Human Rights and End-of-Life Care -- Advance Health Care Directives under European Law and European Biolaw -- Advance Directives Regulation in Italy: Between Consent and Legal Rules -- Patient’s autonomy according to German Law -- “Killing me softly”: new questions about therapeutic self-determination in the Italian society and old answers from the Criminal Code -- The German Law on Euthanasia: the legal basics and the actual debate -- Access to Palliative Care in the Italian Legal System -- Legal Rules on Palliative Care under German Law -- End of Life Care and the Economics of Living Wills -- Appendix.What is the situation of people who are unable to make decisions due to a physical or mental change? This book gives impulses and answers to many ethical, economical and mainly legal questions which arise and are associated with the end of life. A universal human rights approach and the analysis of the relevant European law are put in front of the presentation of the national legal situations in Italy and Germany. The most topical and controversial issues concerning advance care planning are presented as well as a transnational economic analysis on the effects of advance care planning.Veröffentlichungen des Instituts für Deutsches, Europäisches und Internationales Medizinrecht, Gesundheitsrecht und Bioethik der Universitäten Heidelberg und Mannheim,1617-1497 ;41Medical laws and legislationPrivate international lawConflict of lawsPublic healthLaw—EuropeMedical Lawhttps://scigraph.springernature.com/ontologies/product-market-codes/R16005Private International Law, International & Foreign Law, Comparative Law https://scigraph.springernature.com/ontologies/product-market-codes/R14002Public Healthhttps://scigraph.springernature.com/ontologies/product-market-codes/H27002European Lawhttps://scigraph.springernature.com/ontologies/product-market-codes/R20000GermanyItalyGermanyfastItalyfastDeutschlandgndItaliengndMedical laws and legislation.Private international law.Conflict of laws.Public health.Law—Europe.Medical Law.Private International Law, International & Foreign Law, Comparative Law .Public Health.European Law.344.4041Negri Stefaniaedthttp://id.loc.gov/vocabulary/relators/edtTaupitz Jochenedthttp://id.loc.gov/vocabulary/relators/edtSalkić Aminaedthttp://id.loc.gov/vocabulary/relators/edtZwick Annaedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910438226903321Advance Care Decision Making in Germany and Italy2538328UNINA