04361nam 22006975 450 991029864550332120250609111510.03-319-08675-810.1007/978-3-319-08675-0(CKB)3710000000281325(EBL)1968130(OCoLC)908088800(SSID)ssj0001386384(PQKBManifestationID)11896945(PQKBTitleCode)TC0001386384(PQKBWorkID)11374134(PQKB)11337466(MiAaPQ)EBC1968130(DE-He213)978-3-319-08675-0(PPN)183096940(MiAaPQ)EBC6237237(EXLCZ)99371000000028132520141114d2014 u| 0engur|n|---|||||txtccrCarbohydrates as Drugs /edited by Peter H. Seeberger, Christoph Rademacher1st ed. 2014.Cham :Springer International Publishing :Imprint: Springer,2014.1 online resource (242 p.)Topics in Medicinal Chemistry,1862-2461 ;12Description based upon print version of record.3-319-08674-X Includes bibliographical references at the end of each chapters and index.Carbohydrate-Based Synthetic Chemistry in the Context of Drug Design -- Iminosugars: Therapeutic Applications and Synthetic Considerations -- Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs -- Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapagliflozin for the Treatment of Type 2 Diabetes -- Design, Synthesis, and Applications of Galectin Modulators in Human Health -- Discovery and Application of FimH Antagonists -- Carbohydrate-Based Anti-Virulence Compounds Against Chronic Pseudomonas aeruginosa Infections with a Focus on Small Molecules -- The Evolution of a Glycoconjugate Vaccine for Candida albicans.Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.Topics in Medicinal Chemistry,1862-2461 ;12Pharmaceutical chemistryCarbohydratesMolecular biologyMedicinal Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C28000Carbohydrate Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C19030Molecular Medicinehttps://scigraph.springernature.com/ontologies/product-market-codes/B1700XPharmaceutical chemistry.Carbohydrates.Molecular biology.Medicinal Chemistry.Carbohydrate Chemistry.Molecular Medicine.615.3Seeberger Peter H.1966-edthttp://id.loc.gov/vocabulary/relators/edtRademacher Christophedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910298645503321Carbohydrates as Drugs2515820UNINA03655nam 22007335 450 991043804360332120251113182155.09786613943163978128363071912836307109783642308673364230867810.1007/978-3-642-30867-3(CKB)2560000000090988(EBL)994702(OCoLC)801954210(SSID)ssj0000745791(PQKBManifestationID)11421394(PQKBTitleCode)TC0000745791(PQKBWorkID)10859452(PQKB)11205801(DE-He213)978-3-642-30867-3(MiAaPQ)EBC994702(PPN)168317893(EXLCZ)99256000000009098820120717d2013 u| 0engur|n|---|||||txtccr7th International Conference on Knowledge Management in Organizations: Service and Cloud Computing /edited by Lorna Uden, Francisco Herrera, Javier Bajo Pérez, Juan Manuel Corchado Rodríguez1st ed. 2013.Berlin, Heidelberg :Springer Berlin Heidelberg :Imprint: Springer,2013.1 online resource (592 p.)Advances in Intelligent Systems and Computing,2194-5365 ;172Includes author index.9783642308666 364230866X Innovation in Knowledge Management -- Knowledge Management in Business -- - Knowledge Management in Education -- Knowledge Management in the Internet age -- Knowledge Management and Service Science -- Technology applied to Knowledge Management -- Applications of Knowledge Management -- Special Session on Cloud Computing: Advances and Applications.The seventh International Conference on Knowledge Management in Organizations (KMO) brings together researchers and developers from industry and the academic world to report on the latest scientific and technical advances on knowledge management in organisations. KMO 2012 provides an international forum for authors to present and discuss research focused on the role of knowledge management for innovative services in industries, to shed light on recent advances in cloud computing for KM as well as to identify future directions for researching the role of knowledge management in service innovation and how cloud computing can be used to address many of the issues currently facing KM in academia and industrial sectors. The conference took place at Salamanca in Spain on the 11th-13th July in 2012.Advances in Intelligent Systems and Computing,2194-5365 ;172Computational intelligenceArtificial intelligenceApplication softwareComputational IntelligenceArtificial IntelligenceComputer and Information Systems ApplicationsComputational intelligence.Artificial intelligence.Application software.Computational Intelligence.Artificial Intelligence.Computer and Information Systems Applications.658.4/038Uden Lorna1946-1740634International Conference on Knowledge Management in Organizations: Service and Cloud ComputingMiAaPQMiAaPQMiAaPQBOOK99104380436033217th International Conference on Knowledge Management in Organizations4188435UNINA