03086nam 2200625 a 450 991043802230332120200520144314.01-283-61268-297866139251383-7091-1125-010.1007/978-3-7091-1125-3(CKB)2670000000251510(EBL)973350(OCoLC)809934165(SSID)ssj0000737123(PQKBManifestationID)11455688(PQKBTitleCode)TC0000737123(PQKBWorkID)10782288(PQKB)10676934(DE-He213)978-3-7091-1125-3(MiAaPQ)EBC973350(PPN)168331276(EXLCZ)99267000000025151020120727d2013 uy 0engur|n|---|||||txtccrDrug resistance in leishmania parasites consequences, molecular mechanisms and possible treatments /Alicia Ponte-Sucre, Emilia Diaz, Maritza Padron-Nieves, editors1st ed. 2013.New York Springer20131 online resource (457 p.)Description based upon print version of record.3-7091-1706-2 3-7091-0238-3 Includes bibliographical references and index.pt. 1. Determinant features in leishmaniasis -- pt. 2. Leishmania and the immune system -- pt. 3. Challenges in the diagnosis, treatment and control of leishmaniasis in times of drug resistance -- pt. 4. Molecular features of drug-resistant leishmania -- pt. 5. Pharmacology and chemotherapy of leishmaniasis -- pt. 6. Strategies to circumvent drug resistance in leishmania.One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.LeishmaniaParasitesLeishmania.Parasites.616.9616.9/364Diaz Emilia1755275Padron-Nieves Maritza1755276Ponte-Sucre Alicia1755277MiAaPQMiAaPQMiAaPQBOOK9910438022303321Drug resistance in leishmania parasites4192003UNINA