03408nam 2200577Ia 450 991043783430332120200520144314.094-007-6467-710.1007/978-94-007-6467-5(CKB)2670000000372385(EBL)1697553(OCoLC)843401902(SSID)ssj0000894263(PQKBManifestationID)11932485(PQKBTitleCode)TC0000894263(PQKBWorkID)10834885(PQKB)11223636(DE-He213)978-94-007-6467-5(MiAaPQ)EBC1697553(PPN)170494764(EXLCZ)99267000000037238520130522d2013 uy 0engur|n|---|||||txtccrAngiogenesis modulations in health and disease practical applications of pro-and anti-angiogenesis targets /Shaker A. Mousa, Paul J. Davis, editors1st ed. 2013.Dordrecht ;New York Springerc20131 online resource (209 p.)Description based upon print version of record.94-017-8515-5 94-007-6466-9 Includes bibliographical references and index.Preface -- Angiogenesis assays: an appraisal of current techniques -- Survey of pro-angiogenesis strategies -- Angiogenesis modulation by arachidonic acid – derived lipids: positive and negative regulators of angiogenesis -- Pro-angiogenic activity of thyroid hormone analogues: Mechanisms, physiology and clinical prospects -- Actions of steroids and peptide hormones on angiogenesis -- Role of non-neuronal nicotinic acetylcholine receptors in angiogenesis modulation.-  Catecholamine neurotransmitters: an angiogenic switch in the tumor microenvironment -- Impact of nanotechnology on therapeutic angiogenesis -- Survey of anti-angiogenesis strategies -- Tetraiodothyroacetic acid (tetrac), nanotetrac and anti-Angiogenesis -- Integrin antagonists and angiogenesis -- Anti-angiogenesis therapy as an adjunct to chemotherapy in oncology -- Anti-vegf strategies in ocular angiogenesis- mediated disorders, with special emphasis on age-related macular degeneration -- Application of nanotechnology to targeting tumor angiogenesis for therapeutic benefit -- Biomarkers of response and resistance to anti-angiogenic treatment -- Speculations on new directions in which angiogenesis may proceed. Index. This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.NeovascularizationBlood vesselsGrowthNeovascularization.Blood vesselsGrowth.610Mousa Shaker A556586Davis Paul J1763139MiAaPQMiAaPQMiAaPQBOOK9910437834303321Angiogenesis modulations in health and disease4203427UNINA