02882nam 2200613 a 450 991043782810332120200520144314.01-283-93540-63-642-34617-010.1007/978-3-642-34617-0(CKB)2670000000309174(EBL)1082826(OCoLC)823386668(SSID)ssj0000810572(PQKBManifestationID)11439148(PQKBTitleCode)TC0000810572(PQKBWorkID)10833168(PQKB)10794493(DE-He213)978-3-642-34617-0(MiAaPQ)EBC1082826(PPN)168327260(EXLCZ)99267000000030917420130111d2013 uy 0engur|n|---|||||txtccrCalcium signalling approaches and findings in the heart and blood /Lars Kaestner1st ed. 2013.Berlin Springer20131 online resource (246 p.)Description based upon print version of record.3-642-34616-2 Includes bibliographical references and index.Summary -- Calcium Signalling Methodology -- Calcium Signalling in Cardiac Myocytes -- Calcium Signalling in Red Blood Cells -- Index.The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance.CalciumPhysiological effectResearchMethodologyCalciumAnalysisSecond messengers (Biochemistry)ResearchMethodologyCellular signal transductionResearchMethodologyCalciumPhysiological effectResearchMethodology.CalciumAnalysis.Second messengers (Biochemistry)ResearchMethodology.Cellular signal transductionResearchMethodology.572.516Kaestner Lars1060481MiAaPQMiAaPQMiAaPQBOOK9910437828103321Calcium signalling2513700UNINA