03954nam 2200601 450 991043779660332120210310195206.094-007-6232-110.1007/978-94-007-6232-9(CKB)3390000000037216(DE-He213)978-94-007-6232-9(SSID)ssj0000880149(PQKBManifestationID)11467985(PQKBTitleCode)TC0000880149(PQKBWorkID)10873315(PQKB)10435202(MiAaPQ)EBC3091964(MiAaPQ)EBC6413378(Au-PeEL)EBL3091964(CaPaEBR)ebr10962520(OCoLC)839438584(PPN)169142396(EXLCZ)99339000000003721620210310d2013 uy 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierAdvancing methods for biomolecular crystallography. /Randy Read1st ed. 2013.New York, New York :Springer,[2013]©20131 online resource (XIII, 362 p. 131 illus.)NATO Science for Peace and Security Series A: Chemistry and Biology,1874-6489Bibliographic Level Mode of Issuance: Monograph94-007-6231-3 Part I  Solution Chemistry -- Simple Alkoxide Based Precursor Systems -- Carboxylate Based Precursor Systems -- Mixed Metallo-Organic Precursor Systems -- Single Source Precursor Approach -Hydrolysis Mechanisms in Organic Media -- Aqueous Precursor Systems -- Polymer-Assisted Deposition (PAD) -- Part II Analytical Methods -- Thermal Analysis -- X-ray Absorption Spectroscopy -- Infrared Spectroscopy -- Part III  Deposition Techniques -- Dip Coating -- Spin Coating: Art and Science -- Aerosol Deposition -- Inkjet Printing and Other Direct Writing Methods -- Chemical Bath Deposition -- Part IV Processing and Crystallization.-   Thermodynamics and Heating Processes -- Epitaxial Films -- Orientation and Microstructure Design -- Low-Temperature Processing -- Composite Film Processing -- UV and E-Beam Direct Patterning of Photosensitive CSD Films -- Template Controlled Growth -- Part V Functions and Applications -- Thin Film Multilayer Capacitors -- Base Metal Bottom Electrodes -- Polar Oxide Thin Films for MEMS Applications -- Conducting oxide thin films -- Transparent Conducting Oxides.-  Superconducting Films -- Antireflective Coatings and Optical Filters -- Luminescent Thin Films: Fundamental Aspects and Practical Applications -- Appendix – Syntheses.This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web.  Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis.  These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome.  Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.NATO Science for Peace and Security Series A: Chemistry and Biology,1874-6489CrystallographyAnalytical biochemistryCrystallography.Analytical biochemistry.548Read Randy1065189MiAaPQMiAaPQMiAaPQBOOK9910437796603321Advancing methods for biomolecular crystallography2543706UNINA