03548nam 22006735 450 991043762180332120200706091836.01-4614-4660-01-299-19720-510.1007/978-1-4614-4660-6(CKB)2670000000529989(EBL)1081850(OCoLC)826853733(SSID)ssj0000878962(PQKBManifestationID)11560822(PQKBTitleCode)TC0000878962(PQKBWorkID)10850323(PQKB)11009698(DE-He213)978-1-4614-4660-6(MiAaPQ)EBC1081850(PPN)168300850(EXLCZ)99267000000052998920130109d2013 u| 0engur|n|---|||||txtccrGenetic and Molecular Epidemiology of Multiple Myeloma[electronic resource] /edited by Suzanne Lentzsch1st ed. 2013.New York, NY :Springer New York :Imprint: Springer,2013.1 online resource (130 p.)Description based upon print version of record.1-4614-4659-7 1-4899-9865-9 Includes bibliographical references and index.Preface -- Genetics of Multiple Myeloma -- Gene expression signature in MGUS and multiple myeloma -- Cap-Dependent Protein Translation Initiation in Multiple Myeloma: an Attractive Target for Therapy -- IRES-dependent, CAP-independent translation in Multiple Myeloma -- Epigenetic gene silencing as a new target for multiple myeloma -- Role of Bone Disease in the Pathogenesis of Multiple Myeloma -- Index.This state-of-the-art book is written by a group of international experts to provide insight into the newest breakthroughs from basic pathogenesis to clinical aspects of multiple myeloma. The book provides a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.  Areas, which are covered include the characterization of different myeloma entities by genomics and proteomics, notch signaling and targeting protein translation as a new treatment for multiple myeloma, cell cycle control of plasma cell differentiation, the role of bone disease in the pathogenesis of multiple myeloma as well as the molecular interaction of multiple myeloma with a microenvironment. Genetic and Molecular Epidemiology of Multiple Myeloma is a valuable resource for cancer researchers, medical, surgical, and radiation oncologists.Cancer researchCell biologyHuman geneticsCancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Cell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Human Geneticshttps://scigraph.springernature.com/ontologies/product-market-codes/B12008Cancer research.Cell biology.Human genetics.Cancer Research.Cell Biology.Human Genetics.571.6599935610611.01816Lentzsch Suzanneedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910437621803321Genetic and Molecular Epidemiology of Multiple Myeloma2530768UNINA