02991nam 2200553Ia 450 991043761650332120200520144314.01-4614-7729-810.1007/978-1-4614-7729-7(CKB)2670000000406487(EBL)1398469(SSID)ssj0000958031(PQKBManifestationID)11530666(PQKBTitleCode)TC0000958031(PQKBWorkID)10985070(PQKB)10412919(DE-He213)978-1-4614-7729-7(MiAaPQ)EBC1398469(PPN)172419816(EXLCZ)99267000000040648720130731d2013 uy 0engur|n|---|||||txtccrAdvances in HIV-1 assembly and release /Eric O. Freed, editor1st ed. 2013.New York Springer20131 online resource (229 p.)Description based upon print version of record.1-4899-9563-3 1-4614-7728-X Includes bibliographical references and index.Structural Biology of HIV Assembly -- Cellular Trafficking Mechanisms in the Assembly and Release of HIV -- Packaging of the HIV-1 RNA Genome -- Synthesis of Functional and Variable HIV-1 Envelope Glycoproteins -- HIV-1 Budding -- HIV-1 Maturation -- Cell-to-Cell Transmission of HIV -- Virus Assembly as a Target for Antiretroviral Therapy.Over the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle.  This has been made possible by major advances in cell biology, virology, and structural biology.  The field continues to move forward rapidly, with important new discoveries being reported on a regular basis.  The impact of this progress across a broad spectrum of biomedical research has been substantial.  The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research.  The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.HIV (Viruses)Medical virologyHIV (Viruses)Medical virology.616.979201Freed Eric O1755404MiAaPQMiAaPQMiAaPQBOOK9910437616503321Advances in HIV-1 assembly and release4192176UNINA