02760nam 2200589Ia 450 991043761030332120200520144314.01-4614-4705-410.1007/978-1-4614-4705-4(CKB)2670000000232471(EBL)994125(OCoLC)805397222(SSID)ssj0000741030(PQKBManifestationID)11420588(PQKBTitleCode)TC0000741030(PQKBWorkID)10720204(PQKB)10482036(DE-He213)978-1-4614-4705-4(MiAaPQ)EBC994125(PPN)168300974(EXLCZ)99267000000023247120120831h20122013 uy 0engur|n|---|||||txtccrGenome-wide prediction and analysis of protein-protein functional linkages in bacteria /Vijaykumar Yogesh Muley, Vishal Acharya1st ed. 2013.New York, NY Springer2012, c20131 online resource (65 p.)SpringerBriefs in systems biology,2193-4746Description based upon print version of record.1-4614-4704-6 Includes bibliographical references.Introduction -- From genomes to protein functions -- Co-evolutionary signals within genome sequences reflect functional dependence of proteins -- Chromosomal proximity of genes as an indicator of functional linkage -- Analyses of complex genome-scale biological networks -- Applications of protein interaction networks.Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus on protein-protein interaction predictions in bacteria. The authors will describe these methods and further highlight its use to predict various biological pathways and complexity of the cellular response to various environmental conditions. Topics include analysis of complex genome-scale protein-protein interaction networks, effects of reference genome selection on prediction accuracy, and genome sequence templates to predict protein function.SpringerBriefs in Systems Biology,2193-4746 ;2Functional genomicsProtein-protein interactionsFunctional genomics.Protein-protein interactions.572.86Muley Vijaykumar Yogesh1060479Acharya Vishal1761249MiAaPQMiAaPQMiAaPQBOOK9910437610303321Genome-wide prediction and analysis of protein-protein functional linkages in bacteria4200576UNINA